SLE Flashcards
1
Q
Most common cardiac manifestation of SLE
A
Pericarditis (20%)
2
Q
Most common Pulmonary Manifestation of SLE
A
Pleuritis (30-60%)
3
Q
Antiphospholipid Syndrome Antibodies and manifestations of the syndrome
Management
A
Anticardiolipin
Lupus anticoagulant
Anti-beta2-glycoprotein
Miscarriage VTE Livedo Reticularis Valvular Heart Disease Renal disease
Anticoagulation
4
Q
Kidney Disease associated with SLE
Diagnosis
Management
A
Lupus Nephritis - haematuria and proteinuria and casts
Steroids and Imunosuppression (Cyclophosphamide or Mycophenalate)
Renal Biopsy
Monitor Renal Function
Urinary Protein
Urinalysis
5
Q
Classes of Lupus Nephritis, presentation and management
A
Class 1
6
Q
Autoantibodies associated with SLE
- most sensitive test?
- most specific test?
A
These tests are immunofluorescence
ANA (anti nuclear antibodies) - sensitive
- higher titres = mor significant >1:80
dsDNA - specific
Anti-Ro (SSA) -
