SLE Flashcards
1
Q
Hx 1
A
- F, 20-40yo
- Hx of CNS involvement
- psychosis
- seizures
- cognitive dysfunction
- HA
- Hx of GIT involvement
- Bleeding
- Diarrhoea
- Fatigue
- LoW
- Fever
2
Q
SSx- Vitals
A
- Fever
* Incr. HR (d/t haemolytic anaemia)
3
Q
SSx- Skin & Hair
A
- Malar Rash:
- Fixed erythema; flat or raised; spares the nasolabial folds
- Discoid rash (30% of patients):
- Red raised patches with adherent keratosis & scarring
- Photosensitivity
- Skin ulceration (d/t vasculitis & basement membrane Ag-Ab complex deposition)
- Evidence of haemorrhage:
- Purpura i.e. nonblanching red lesions on fingers & palms (d/t to vasculitis)
- Petechial haemorrhage - thrombocytopenia
- Bruising (larger) - Clotting factor deficiency
- Alopecia: (40%) non-scarring, usually reversible
4
Q
SSx- Mouth
A
- oral / nasopharyngeal ulcers
* bleeding gums (pupuric lesion)
5
Q
SSx- MSK
A
- Mm Pain (d/t inflammatory myopathy)
- Synovitis
- non-erosive
- 2 peripheral joints
(Most common: fingers, wrists, knees, toes; less common: elbows, shoulders, ankles) - symmetrical
- morning stiffness
6
Q
SSx- Serositis
A
- Pleuritis:
- pain
- pleural rub
- effusion
- Pericarditis:
- rub
- effusion
- precordial pain
7
Q
SSx- Kidneys
A
- lupus nephritis
- palpation of kidneys if renal involvement suspected
8
Q
SSx- CNS & PNS
A
- affected by vasculitis &/or direct Ab attack
- PNS
- CN Exam for nerve palsy
- CNII, III, IV, VI
- Upper MN Exam
9
Q
SSx- Haematological
A
- Haemolytic Anaemia
- Lymphopaenia
- Thrombocytopaenia
- Leukopaenia
10
Q
SSx- Vasculitis
A
- Haemorrhage main manifestation
- Pupuric skin lesion (gums, retinal haemorrhage)
- digital gangrene
- telangiectases in nail fold
- Reynauds
11
Q
SSx- Cardiac 1
A
- Endocarditis
- Symptoms
- fatigue
- Fever
- Chills
- HA
- SOB
- Signs
- Anaemia
- SOB
- heart murmurs
- LEX oedema
12
Q
SSx- Cardiac 2
A
- Myocarditis
- Symptoms:
- Precordial pain
- SOB
- fatigue
- Signs:
- arrythmia
- LEX oedema
- Murmurs
13
Q
SSx- Lymphoid System
A
- hyperplasia, resulting in:
- lymphadenopathy
- splenomegaly
