PMDM Exam Flashcards

1
Q

Hx 1

A
  • DM has all SSx of PM with skin manifestations added
  • F>M, 5-15yo / 40-60yo
  • Dz association with neoplasm and increased Ca risk (esp. with DM)
  • SSx onset preceded by acute infection
  • onset acute in children
  • onset insidious in adults
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2
Q

SSx- Systemic

A
  • low grade fever
  • fatigue
  • LoW
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3
Q

SSx- MSK

A
  • affects proximal girdle Mm
  • weakness
  • symmetrical
  • Mm pain / ache / tenderness
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4
Q

SSx- Viscera

A
  • Pharynx & upper esophagus:
  • affects swallowing,
  • predisposing to aspiration
  • Lungs:
  • interstitial pneumonitis:
  • dyspnea and cough
  • Heart:
  • arrhythmias
  • GIT:
  • haematemesis
  • melena
  • ischaemic bowel perforation
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5
Q

SSx- Skin 1 (in DM)

A
  • in DM Pts only!
  • Rash:
  • often = the first manifestation;
  • may be pruritic dusky (bluish-purple) and erythematous
  • slightly elevated patches
  • smooth or scaly
  • Distribution:
  • forehead
  • V of the neck and shoulders
  • forearms and lower legs
  • radiodorsal surface of PIP’s & MCP’s
  • chest and back
  • elbows and knees
  • medial malleoli
  • Gottron’s papules :
  • Slightly elevated, violaceous papules & plaques, occurring over bony prominences
  • pathognomonic
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6
Q

SSx- Skin 2 (in DM)

A
  • Periorbital edema + heliotrope (purplish) rash on eyelids;
  • pathognomonic for DM
  • Desquamating dermatitis with splitting of the skin over the radial aspects of the fingers
  • Subcutaneous calcification (calcinosis): esp. in children; presents as hard lumps
  • Raynaud’s syndrome: occurs in response to cold or emotional upset
  • The primary skin lesions frequently fade completely but may be followed by 2ary changes:
  • brownish pigmentation
  • atrophy
  • scarring
  • vitiligo
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7
Q

SSx- Nails (in DM)

A
  • The base and sides of the fingernails red or thickened

* telangiectases in proximal nail fold

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8
Q

SSx- Articular

A
  • Mild arthralgia & inflammation (30%)

* Small joints of the hands are the most frequently involved

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