PMDM Exam Flashcards
1
Q
Hx 1
A
- DM has all SSx of PM with skin manifestations added
- F>M, 5-15yo / 40-60yo
- Dz association with neoplasm and increased Ca risk (esp. with DM)
- SSx onset preceded by acute infection
- onset acute in children
- onset insidious in adults
2
Q
SSx- Systemic
A
- low grade fever
- fatigue
- LoW
3
Q
SSx- MSK
A
- affects proximal girdle Mm
- weakness
- symmetrical
- Mm pain / ache / tenderness
4
Q
SSx- Viscera
A
- Pharynx & upper esophagus:
- affects swallowing,
- predisposing to aspiration
- Lungs:
- interstitial pneumonitis:
- dyspnea and cough
- Heart:
- arrhythmias
- GIT:
- haematemesis
- melena
- ischaemic bowel perforation
5
Q
SSx- Skin 1 (in DM)
A
- in DM Pts only!
- Rash:
- often = the first manifestation;
- may be pruritic dusky (bluish-purple) and erythematous
- slightly elevated patches
- smooth or scaly
- Distribution:
- forehead
- V of the neck and shoulders
- forearms and lower legs
- radiodorsal surface of PIP’s & MCP’s
- chest and back
- elbows and knees
- medial malleoli
- Gottron’s papules :
- Slightly elevated, violaceous papules & plaques, occurring over bony prominences
- pathognomonic
6
Q
SSx- Skin 2 (in DM)
A
- Periorbital edema + heliotrope (purplish) rash on eyelids;
- pathognomonic for DM
- Desquamating dermatitis with splitting of the skin over the radial aspects of the fingers
- Subcutaneous calcification (calcinosis): esp. in children; presents as hard lumps
- Raynaud’s syndrome: occurs in response to cold or emotional upset
- The primary skin lesions frequently fade completely but may be followed by 2ary changes:
- brownish pigmentation
- atrophy
- scarring
- vitiligo
7
Q
SSx- Nails (in DM)
A
- The base and sides of the fingernails red or thickened
* telangiectases in proximal nail fold
8
Q
SSx- Articular
A
- Mild arthralgia & inflammation (30%)
* Small joints of the hands are the most frequently involved