SLE

Question 1

First visit Pregnancy blood work

Answer 1

First visit — At the first visit after (or at which) pregnancy is confirmed, the following investigations are recommended
• Physical examination, including blood pressure
• Renal function — glomerular filtration rate, urinalysis, urine protein/urine creatinine ratio
• Complete blood count
• Anti-Ro/SSA and anti-La/SSB antibodies
• LA (lupus anticoagulant) and aCL (anti-cardiolipin) assay
• Anti-double stranded DNA antibodies
• Complement (CH50, or C3 and C4)
• Uric acid level
In the absence of any historical features of the APS (eg, recurrent pregnancy loss, venous or arterial thromboembolism), we recommend that patients with high levels of aCL or the presence of an LA receive low dose ASA therapy, although the data regarding the management of these patients is equivocal. Women with lupus and the APS require more frequent monitoring than those with SLE alone.

Question 2

Post partum complication serological marker

Answer 2

anti-Ro/SSA anti-la

causing fetal heart block