SLE

Question 1

What is SLE-type arthritis like?

Answer 1

non-erosive (unlike RA)

Question 2

If patient has mouth lesions in SLE, are they painful or non-painful?

Answer 2

Always non-painful, otherwise they are due to another cause such as viral.

Question 3

What are some main tests that can be used for diagnosing SLE?

Answer 3

ANA

DNA

Question 4

Is ANA specific? sensitive?

Answer 4

100% sensitive, but not specific

Question 5

Is the SLE DNA test specific? sensitive?

Answer 5

Not very sensitive, but it is ~98% specific

Question 6

What can be a lung complication of SLE?

- how would you treat it?

Answer 6

Hemorrhage - treat with Cytoxan

Question 7

What are some kidney complications of lupus?

Answer 7

Glomerulonephritis
Nephrotic Syndrome
Proteinuria

Question 8

How does CNS lupus present?

Answer 8

Seizures, psychosis

Question 9

What cells are affected in lupus?

Answer 9

B-cells

Question 10

What are some SLE criteria?

Answer 10

• Malar rash (spares the nasolabial fold)
• Dyscoid lesions (scalp)
• Photosensitivity
• Arthritis
• Serositis
• Renal Disorder
• ANA
• DNA

Question 11

What is the main non-pharmacological treatment for SLE?

Answer 11

Avoid sun