Skin, wounds, eyes Flashcards
List all the 10 Anatomical parts of the SKIN.
- Keratin
- Sweat Duct
4,5 Blood Vessels - Nerves
- Subcutaneous layer
- Dermis
- Epidermis
Factors which control microbial load on SKIN
- limited amount of moisture
- Acid ph
- Surface temp is lower than optimal for most pathogens
- high salt concentration
chemical with antibacterial properties ex. sebum, fatty, acids, urea - competitive inhibition from normal flora
Three lines of Attack
- Disseminated infection localises in skin ex chicken pox, measles, exogenous infection
- Transient/normal flora exploits breach in skin ex. endogenous infection, abrasions. surgery, burns, may disseminate from local primary infection
- Toxin production enables tissue damage/ inflammation ex. scarlet fever
How do skin breach by skin loving organisms?
- Resident flora able to resist high salt concentration
- Host factors encourage transmission and inoculation
- organism contains toxins that cause acute inflammation.
Used to survive phagocytosis and kill neutrophils
Catalase
Cause abscess formation
Coagulase
Cause to damage to cell membranes
Alpha & beta shore forming toxins
Explain FOLLICULTIS
Description: Boils and Carbuncles Entry: via hair follicles Bacteria: Staphylococcus aureus Can get from: abrasions/breaches Classified as: Endogenous/exogenous infections
Explain IMPETIGO (Bullous form)
Bacteria: Staphylococcus aureus
Affected area: limbs and buttocks
can get from: skin exposure & insect bites
classified as: microbiology diagnosis
Explain IMPETIGO (non-bullous form)
Bacteria: Streptococcus pyogenes
description; brown rough texture on skin
common in: children (face)
Explain ERYSIPELAS
Bacteria: Streptococcus pyogenes
description; small red lesions, demarcate edge
treatment: antimicrobial therapy
explain CELLULITIS
Type: Acute bacterial infection Bacteria: Streptococci spp & staphylococcus aureus additional info; -haemophilus influenza Type B -clostridium perfinges -fever chill ln enlargement
Explain ACNE
Bacteria: Propionibacterium acnes
-increase sebum and keratinisation
Portal of entry for WOUND INFECTION
- surgical
- burns
- trauma
Give the 6 types of SKIN BACTERIAL INFECTION
- Folliculitis
- Impetigo bullous form
- Impetigo non-bullous form
- Erysipelas
- Cellulitis
- Acne
Bacteria you can get in CLEAN WOUNDS
- Staphylococcus aureus
2. Enterobacteria
Bacteria you can get from ABDOMINAL WOUNDS
- Staphylococcus aureus
- enterobacteria
- anaerobes & entercocci
Portal of Entry via Intravenous Catheters
-staphylococcus aureus
-staphylococcus epidermis
corynebacterium jeikeium
Portal of entry via PRESSURE SORES
- staphylococcus aureus
- streptococcus pyogenes
- enterobacteria/ enterococci
how can you get wound infection from surgery
- operating room
- hands
- patient’s flora
Portal of entry via TRAUMA/BURNS
- skin/environmental flora
- melioidosis
- pseudomonas spp
- soil gnb
portal of entry via TRAUMA
- Endospores
- tissues low oxygen tissues
anaerobic bacteria
-clostridium perfringes
It is called as the “skin loving fungi”
Dermatophytes
Explain the 3 characteristics of DERMATOPHYTES
- Geophilic, zoophilic, anthropophilic
- Continuous moist skin
- cause inflammation