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Tissue Biology > Skin (W2) > Flashcards

Skin (W2) Flashcards

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1
Q

What are the 3 layers of the skin

A
  1. hypodermis
  2. dermis
  3. epidermis
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2
Q

Describe the hypodermis

A
  • mature adipose tissue
  • compartmentlaised by fibrous speta
  • thickmness & degree of compartmentalisation
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3
Q

Describe the dermis

A
  • buddles of collsgen fibres and strands of elastic fibres
  • small amount of aceullar ground substance
  • 2 layers
    1. Reticular
    2. Papillary
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4
Q

Describe the epidermis and its function

A
  • outermost layer
  • thickest
  • protection from the outside world
  • metabolic (lipid storage)
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5
Q

What are the 5 layers of the epidermis from the bottom

A
  1. stratum basale
  2. stratum spinosum
  3. stratum granulosum
  4. stratum corenum
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6
Q

Descrribe the strtaum basale

A
  • deepest layer of epidermis
  • new skin cells develop in this layer
  • contains; keratinocytes (produce keratin) & melanoctyes (produce melanin providing pigment)
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7
Q

Describe the stratum spinosum

A
  • contains keratinocytes
  • held together by sticky protein desmosomes
  • helps make skin flexible and strong
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8
Q

Describe the stratum granulosum

A
  • keratin flakes/ plates attached at the edges
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9
Q

Describe the stratum corneum

A
  • top layer we see
  • keratinocytes become corneocytes (string dead keratinocytes protecting us from harm
  • contsins fats that keep water from asily enaterinf of leaving the body
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10
Q

Name the cells of the epidermis and their functions

A
  1. Keratinocytes - produce keratin protective layer
  2. Langerhans cells - APC
  3. Melanocytes - produce melanin protecting us from UV
  4. Merkel cells - rare neuroendocrine cell (sensory)
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11
Q

Descrieb what a hair folicle look sloike in H&E staining

A
  • compsoed of several layers
  • always associated with sebaceous glands and arrector pili
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12
Q

What are sebaceous glands

A
  • secret sebum (oily substance)
  • holocrine mechansim of secretion
  • lubricates the hair and skin
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13
Q

Structure

Describe eccrine sweat glands & ducts

A
  • highly coiled and straight
  • outer layer of contractile cells (myoepithelial cells)
  • secret sweat - mostly water, sodium & chloride uons, urea
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14
Q

What are the functions of ther skin

A
  • protection from mutiple external threats
  • moistire contorl
  • immunological/antigen presentation
  • thermoregulation
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15
Q

What are the fiunctions of eccrine glands

A
  • thermoregulation
  • excretory
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16
Q

What layer is only present in thick skin

A

stratum lucidem

17
Q

what are Merkel calls

A

act as touch receptors

Tissue Biology (6 decks)

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