Skin - principles, congenital disorders Flashcards
Therapy of juvenile localised demodicosis
- spontaneous healing (up to 90%)
- no need for acaricid therapy, if small amounts of mites, but followup in every two weeks
- if many mites: shampooing with follicular flushing effect: benzoyl-peroxide. + registered spot on Advocate (moxidectin) in every 4-2 weeks
therapy of generalized demodicosis
- intense therapy + immunostimulation
- not registered by now: flusjing with amitraz 250-600 ppm in every 7-14 days
Therapy of feneralized demodicosis registered per os:
- fluralaner (metabolised in liver), afoxolaner (metabolised in kidney), sarolaner (metabolised in liver), lotilaner (metabolised in liver)
Use of antibiotics in pyoderma:
- emirical
first line:
- Cefalexin 2*30mg/kg: dont influence gut lora, narrow spectrum, but takes staph.
- Cefadroxil 2*22mg/kg
- (clindamycin, likomycin, szulfadimetoxin)
Use of antibiotics in pyoderma:
- based on resistance:
- amox - clavulon
- cefovecin
antifungal therapy
Topically:
- imaverol solution, malaseb shampoo AUV
Systematically:
- itrakonazole (microsporum, candida, malassezia, aspergillus, leishmania, trypanosoma)
- terbinafin 8trichophyton)
- fluconazole (fungal meningitis and oral candida)
Alopecia
- “Black hair follicle dysplasia”
Occurrence:
- bearded collie, dachshound, papillon, basset
Clinical signs:
- from 4 weeks hairs fall out, fail to grow, scaling
Diagnosis:
- skin biopsy (abnormal follicles, with keratine plugs)
Treatment:
- antiseborrheoic shampoo (selenium disulphide, benzoyl peroxyde)
Alopecia
- Color mutant alopecia
“blue dobermann syndrome”, “blue dog disease”
Occurrence:
- in red and beige (fawn) dobermann, fawn irish setter + blue individuals of some other breeds
Clinical signs:
- at 1-3 years “moth eaten” alopecia on the back parts of the coat + increased scale + papule formation
Diagnosis:
- skin biopsy (cystic hair follicles filled with keratin)
Alopecia
- pattern alopecia Dachshound:
- bilateral alopecia of the pinnae (males)
- ventral alopecia (females)
- no response to treatment
Alopecia:
- melanoderma and alopecia of yorkshire
- onset at 6months-3years (both sex)
- occurs at the nose and legs
- spontaneous recovery is possible
Types of Alopecia:
- Generalized (normal, pathological, naturally)
- Hypotrichosis (siemese, devon rex cat)
- Black hair follicle dysplasia
- color mutant alopecia
- pattern alopecia: dachs
- melanoderma and alopecia in yorkshire
Types of Congenital pigmentation defects
- Hereditary vitiligo
- canine cyclic hematopoesis (grey collie syndrome)
- tyrosinase deficiency in the chow-chow
Congenital pigmentation defects
- Hereditary vitiligo
Occurrence:
- GS, belgian shepherd, rottweiler, dobermann, old english shepherd, dachshund
Clinical signs:
- hypopigmentation on the nose, lip, buccal mucosa, facial skin, footpads, nails
Congenital pigmentation defects
- canine cyclic hematopoesis (grey collie syndrome)
Occurence: 6-12weeks
Clinical signs:
- pyrexia, lymphadenopathy, nonregenerative anemia, arthralgia, diarrhea
Course: lethal
Congenital pigmentation defects
- tyrosinase deficiency of Chow-chow
- Cause: impared melanin synthesis
- occurs in puppies: pink tounge, hair shafts turh white
- sp. recovery