Skin Morphology Flashcards

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1
Q

Name the four layers of the epidermis

A

Basal, Prickle, Granular, Keratin

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2
Q

What is the name of the developmental pattern of skin growth?

A

Blaschkos lines

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3
Q

What protein is expressed in the granular layer that ensures the skin stays moisturised?

A

Fillagrin

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4
Q

What is the definition of a scar?

A

The loss of appendages, no hair or sweat glands

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5
Q

Dermo epidermal junction

A

Interface between dermis and epidermis

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6
Q

What is the DEJ broken down into?

A

Lamina Lucida, Lamina Densa, Sub lamina densa.

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7
Q

What glands secrete sweat?

A

Eccrine

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8
Q

What glands secrete pheromones?

A

Apocrine

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9
Q

What glands are found at the base of the hair follicles

A

Sebaceous

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10
Q

What is the function of melanocytes?

A

Produce melanin which is secreted into the cells to protect them from UV

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11
Q

What does melanin do?

A

Absorbs UV radiation

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12
Q

Where are melanocytes found?

A

They cap the basal cells to protect the DNA

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13
Q

What are Basal cells?

A

Located superiorly to the DEJ, these are the stem cells of the skin proliferation and differentiation occur from these cells.

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14
Q

What granule can be used to identify langerhaan cells?

A

Birbeck granule, tennis racket shape

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15
Q

What is the function of langerhaan cells?

A

They are a subtype of dendritic cells.

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16
Q

What are the downward projection of the epidermis into the dermis called?

A

Rete ridges.

17
Q

What cell make up the epidermis?

A

Stratified Squamous epithelium

18
Q

What is a pilosebaceous unit?

A

A hair follicle and the sebaceous gland

19
Q

What in hair is the growing phase?

A

Anagen

20
Q

How long does Anagen last?

A

5-7 years

21
Q

What in hair is the resting phase?

A

Telogen

22
Q

What in hair is the involution phase?

A

Catagen

23
Q

What occurs in the Catalan phase?

A

Hair degenerates and falls out

24
Q

What hormones cause hair growth?

A

Thyroxine and androgens