Immunology

Question 1

How do keratoncytes react to microbes?

Answer 1

They release antimicrobial peptides

Question 2

Which T cells are found in the epidermis?

Answer 2

CD8+ T cells

Question 3

Which T cells are found in the dermis?

Answer 3

CD8+ and CD4+ T cells

Question 4

Which T cells are linked to psoriasis?

Answer 4

TH1 and TH17

Question 5

Which T cells are linked to atopic dermatitis?

Answer 5

TH2

Question 6

How do langerhann cells work?

Answer 6

Act like dendritic cells and bind to microbe
Travel via lymphatic system to lymph nodes
CD4+ T cells with correct fit bind to epitome and produce cytokines
Cytokines trigger B cells in germinal centre to proliferate
CD8+ T cells travel to epidermis

Question 7

TH1 CD4+ cells release what cytokine?

Answer 7

IL2 and IFNY to activate macrogphages

Question 8

TH2 CD4+ cells release what cytokines?

Answer 8

IL4 IL5 IL6 which help B cells to make antibodies

Question 9

MHC 1 Complex

Answer 9

Found on all cells and presenting an endogenous antigen
Used for self cell recognition.
Present to CD8+ T cells

Question 10

MHC II complex

Answer 10

Only found on Antigen presenting cells

Present to CD4+ cells