Skin disorders Flashcards
How many grams of topical cream/ointment are needed for a single application to the hands, head, face, anogenital region?
2 g
How many grams of topical cream/ointment are needed for a single application to one arm, anterior or posterior trunk?
3 g
How many grams of topical cream/ointment are needed for a single application to one leg?
6 g
How many grams of topical cream/ointment are needed for a single application to the entire body?
30-60 g
How many grams of a topical cream/ointment can be expected in one fingertip unit (FTU)?
From very end of the finger to the first crease in the finger
0.5 g
Low potency topical corticosteroids (class V to VII)
- Hydrocortisone (0.5%, 1%, 2.5%)
- Desonide (0.05%)
- Triamcinolone (0.025%, 0.1%)
High potency topical corticosteroid (class II)
Betamethasone dipropionate 0.05%
Super high potency topical corticosteroid (class I)
- Clobetasol propionate 0.05%
- Halobetasol propionate 0.05%
True/false: Topical corticosteroids should not be used longer than 3 months to avoid adverse effects including SQ tissue atrophy
True
First generation vs second generation antihistamines
First generation → diphenhydramine (benadryl)
Second generation → loratidine (claritin), cetirizine (zyrtec), fexofenadine (allegra)
Precautions that should be taken when prescribing first generation antihistamines
Crosses the BBB → sedation
- Caution in geriatrics (drying of secretions, visual changes, urinary retention, used as sleep aid)
What is impetigo?
Contagious skin infection with typical presentation of purulent skin lesions
- Common in children 2-5 years old
- Causative agents: s. aureus, GAS
Impetigo clinical presentation
- Can be bullous or nonbullous
- Honey colored crusting with erythematous base
- Common on face and extremities
Impetigo treatment
- Usually resolves without treatment in 1-2 weeks
- Can consider topical antimicrobial therapy to minimize contagion → mupirocin (bactroban)
True/false: Children with impetigo should be kept out of school or daycare for 24 hours after initiation of antibiotic therapy, and family members should be checked for lesions
True
When can the provider consider using oral therapy for impetigo treatment?
Beta-lactamase (dicloxacillin, amoxicillin-clavulanate) or cephalosporin
- Patients with bullous impetigo
- Have numerous lesions
- Not responding or cannot tolerate topical agents
- During outbreaks
Mild acne classification
- Fewer than 20 comedones
- Fewer than 15 inflammatory lesions
- Total lesion count fewer than 30
Moderate acne classification
- 20-100 comedones
- 15-50 inflammatory lesions
- Total lesion count 30-125
True/false: During acne treatment, patient education should include that improvement will not be seen with medication until 2-4 weeks of therapy is completed
False - will take 4-6 weeks before improvement is seen
Examples of keratolytic/comedolytic agents used for acne treatment
- Tretinoin (Retin-A)
- Should be used with sunscreen due to photosensitivity
- Adapalene
- Tazarotene
Hormonal therapy for acne treatment
- COC pills → suppress ovarian androgen production
- Aldosterone antagonist (spironolactone) → reduces free testosterone
When is isotretinoin (accutane) therapy indicated for acne treatment?
For severe and/or cystic acne that does not respond to conventional therapy
Isotretinoin (accutane) considerations
- Teratogenic → use two forms of contraceptive, avoid sex 1 month after d/c
- Assess for depressed mood, SI
- Monitor for pseudotumor cerebri, hypertriglyceridemia, elevated hepatic enzymes, chelitis
Treatment recommendations for mild acne (comedonal, inflammatory, mixed lesions)
Benzoyl peroxide OR topical retinoid (tretinoin, adapalene, tazarotene)
Treatment recommendations for moderate acne (comedonal, inflammatory, mixed lesions)
Topical combination therapy:
- Benzoyl peroxide + topical antibiotic
- Benzoyl peroxide + retinoid
- Retinoid + benzoyl peroxide + topical antibiotic
Treatment recommendations for severe acne (inflammatory, mixed, and/or nodular lesions)
- Oral antibiotic + topical combination therapy:
- BP + topical antibiotic
- BP + retinoid
- BP + retinoid + topical antibiotic
- Oral isotretinoin
Antibiotic of choice for patients coming in with bite wounds
Amoxicillin with clavulanate
First degree burn classification
Superficial
- Red
- Somewhat painful
- Easily blanched
- Warm to touch
Second degree burn classification
Partial thickness
- Deeply red
- Blistered
- Swollen
- Hot to touch
- Raw
- Moist surface
- Very painful
Deep second degree burn classification
Deep partial thickness
- Involves deep layers of dermis
- Appears white
- Does not blanch
Third degree burn classification
Full thickness
- Whitish
- Charred or translucent
- Not painful
- Affected area lacks pinprick sensation
- Surrounded by painful first and second degree burns
Rule of nines for calculating total burn