Skin Cancer

Question 1

UVB

Answer 1

Carcinogenic
Causes sunburn
Blocked by glass
Photons absorbed directed by DNA

Question 2

UVA

Answer 2

Carcinogenic
Also involved in tanning and wrinkling
Indirect DNA damage through oxidization

Question 3

2 types of melanin

Answer 3

Eumelanin (brown-black)

Phaeomelanin (red)

Question 4

Basal cell carcinoma

Answer 4

Most common
Locally destructive but not usually metastatic
Translucent, telangectasia, papular, can be ulcerated or eroded

Question 5

4 variants of BCC

Answer 5

Superficial spreading
Nodular
Sclerosing
Pigmented

Question 6

Freckles (ephelids)

Answer 6

Secondary to sun damage
Not precancerous
Fade/get stronger depending on sun exposure

Question 7

Seborrheic keratosis

Answer 7

Some texture to it
“stuck on appearance”
Very common
Not precancer

Question 8

Nevi (moles)

Answer 8

Proliferations of abnormal melanocytes

Most acquired ones are secondary to sun damage

Question 9

ABCDEs of melanoma

Answer 9

Asymmetry
Border irregularity
Colour variation
Diameter (> 6 mm)
Enlarging or evolving

Question 10

Superficial spreading melanoma

Answer 10

Often from atypical nevi
Most common type
Irregular edge, colour variation, quite flat until late, often large

Question 11

Nodular melanoma

Answer 11

No precursor lesion

Usually a black nodule

Question 12

Lentigo maligna melanoma

Answer 12

From lentigo maligna
Often on the face
Very slowly progressive as a large flat patch, then a nodule occurs