Skin Abnormalities Flashcards

1
Q

What are the 3 layers of skin?

A
  • Epidermis
  • Dermis: blood vessels, hair follicles, sebaceous glands, sweat glands
  • Subcutaneous
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the appendages of the skin?

A
  • Hair
  • Nails
  • Sebaceous glands
  • Sweat glands
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What do sebaceous glands do and where are they located?

A
  • Produce fatty substance onto skin surface through hair follicles
  • Present on all skin surfaces except palms and soles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the different types of sweat glands and what do they do?

A
  • Eccrine: Widely distributed, open directly onto skin surface, help control body temp (via sweat production)
  • Apocrine: Found chiefly in axillary and genital regions, usually open into hair follicles. Can be stimulated by emotional stress. Bacterial decomposition of apocrine sweat causes body odor
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the key history questions for skin (HPI/ROS)

A
  • Color changes?
  • Rashes?
  • Lumps?
  • Itching?
  • Dryness?
  • Hair and nail changes?
  • Weight changes, fever, chills or difficulty sleeping?
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the differences between Central and Peripheral cyanosis

A
  • Central cyanosis: consistent with cardiac or pulmonary disease
  • Peripheral cyanosis: may be seen with cold temperature or anxiety
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What can be associated with jaundice?

A

Icterus-conjunctivae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the Skin- Color of lesions?

A
  • Flesh-colored: same color as surrounding skin
  • Erythematous: variable shades of red (pink, bright red, dull red)
  • Violaceous: light violet
  • Tan-brown
  • Black or blue-black
  • White
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe the Morphology of Primary and Secondary Lesions

A
  • Primary skin lesions: initial presentation, arise from previously normal skin –> Key to diagnosis
  • Secondary skin lesions: results from changes to primary lesions –> Usually due to overtreatment, scratching or infection of the primary lesion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the Primary skin lesions?

A
  • Flat: Macule or patch
  • Palpable: Papule, plaque, nodule, tumor or wheal
  • Palpable with contents: Vesicle, bulla, pustule or cyst
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe a Macule

A
  • <1 cm diameter
  • Flat, non-palpable
  • Variable color
  • Examples: freckles, petechiae
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe a Patch

A
  • ≥1 cm diameter
  • Flat, non-palpable
  • Irregular shape
  • Examples- Café au lait spots, vitiligo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe a Papule

A
  • <1 cm diameter
  • Palpable, firm
  • Circumscribes
  • Flesh-colored, red, brown
  • May be confluent and form plaques
  • Examples- Molluscum contagiosum, warts, nevi (moles)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe Plaque

A
  • ≥ 1 cm diameter
  • Elevated, firm, rough
  • Circumscribed
  • Example- psoriasis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Describe a Nodule

A
  • ≥ 1 cm but <2 cm diameter
  • Deeper and firmer than a papule (must palpate to determine)
  • Usually round
  • Examples- lipoma, some skin cancers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe a Tumor

A
  • ≥ 2 cm
  • A larger nodule
  • Examples- hemangioma, tumors, lipoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Describe a Wheal

A
  • Irregular, transient, superficial edema

- Examples- mosquito bites, urticaria (hives)/allergic reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Describe a Vesicle

A
  • <1 cm diameter
  • Well-circumscribed
  • Filled with serous fluid
  • Examples- Herpes simplex “Dew drops on a rose petal”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Describe a Bulla (plural = bullae)

A
  • ≥ 1 cm diameter
  • Well-circumscribed
  • Filled with serous fluid
  • Examples- blisters, 2nd degree burns
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Describe a pustule

A
  • Well-circumscribed
  • Elevated, superficial, epidermal
  • Filled with pus
  • Example- acne
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Describe a cyst

A

-Nodule filled with liquid or semisolid material

22
Q

What are the Secondary skin lesions?

A
  • Loss of skin surface- erosion, ulcer or fissure
  • Material on skin surface- scale or crust
  • Other- Excoriation, lichenification or atrophy
23
Q

Describe Erosion

A
  • Loss of superficial epidermis
  • Surfaces is moist but doesn’t bleed
  • Heals without scarring
  • Examples- ruptured vesicle, atopic dermatitis
24
Q

Describe an ulcer

A
  • Deeper loss of epidermis and dermis
  • Heals with scarring
  • Examples- stasis ulcer
25
Q

Describe a fissure

A
  • Linear crack or break from the epidermis to the dermis

- Examples- atopic dermatitis, tinea pedis, angular cheilitis

26
Q

Describe a scale

A
  • A thick flake of exfoliated epidermis

- Examples- seborrhea, psoriasis

27
Q

Describe crust

A
  • Dried residue of serum, pus or blood

- Example- impetigo

28
Q

Describe excoriation

A
  • Abrasion or scratch mark
  • May be linear or rounded
  • Usually due to scratching
  • Examples- scabies, atopic dermatitis, dry skin
29
Q

Describe Lichenification

A
  • Thickening and roughening of the skin
  • Increased visibility of skin markings
  • Examples- atopic dermatitis, chronic dermatitis
30
Q

Describe atrophy

A
  • Thinning of the skin with loss of normal markings
  • Skin looks shinier and more translucent
  • Example- striae (stretch marks)
31
Q

Describe a keloid

A
  • Hypertrophic scarring

- Extends beyond the borders of initial injury

32
Q

What are the Skin Lesions? Describe if they blanch or not.

A

Do NOT blanch

  • Petechiae
  • Purpura
  • Ecchymosis
  • Cherry angioma

Blanch

  • Spider angioma
  • Spider veins
  • Telangiectasia
  • Hemangioma
33
Q

Describe Petechia (pleural = petechiae)

A
  • 0.1-0.3 cm (1-3 mm) diameter
  • Represent blood outside of a vessel
  • Round or irregular
  • Deep red or purple-red
  • Seen with infections and bleeding disorders
  • Do NOT blanch
34
Q

Describe Purpura

A
  1. 3-1 cm
    - Same as petechiae but larger
    - Do NOT blanch
35
Q

Describe Ecchymosis

A
  • Generally >1 cm diameter
  • “Bruise”
  • Represent blood outside of vessels due to trauma, bleeding disorders
  • Round, oval or irregular borders
  • Purple lesions of variable size. Fade to green, yellow, brown
  • Does NOT blanch
36
Q

Describe Cherry angioma

A

1-3 mm diameter

  • Flat or raised
  • Red
  • Non-pulsatile
  • Seen on trunk
  • Associated with aging
  • Do NOT blanch
37
Q

Describe Spider angioma

A
  • Very small up to 2 cm diameter
  • Central body with surrounding erythema, and radiating legs (spider)
  • Seen on face, neck, arm and upper trunk
  • Associated with- liver disease, pregnancy
  • Do blanch
  • A type of telangiectasia
38
Q

Describe Spider veins

A
  • Very small to several inches
  • Variable shape, may resemble spider, be linear or irregular
  • Most often seen on legs (varicose veins)
  • Blanch with diffuse pressure only
39
Q

Describe Telangiectasia

A
  • Irregular lines secondary to dilations of capillaries
  • Red
  • Seen with basal cell skin cancers, sun-damage, rosacea
  • Do blanch
40
Q

Describe Hemangioma

A
  • Irregular lesion secondary to dilation of dermal capillaries
  • Red
  • Starts as a macule, can progress to plaque or nodule
  • Example- “strawberry hemangioma”
41
Q

Describe Maculopapular lesions

A

-Macules with papules
-Examples:
♣ Viral exanthems: generalized, erythematous, maculopapular rash
♣ Drug eruptions

42
Q

Describe Papulosquamous lesions

A

-Papules with plaques and scales
-Examples
♣ Lichen planus
♣ Pityriasis rosea

43
Q

Describe Vesiculobullous lesions

A
  • Vesicles and bullae
  • Examples: Herpes simplex, Herpes zoster, Pemphigus vulgaris, Serious autoimmune disease affecting skin and mucous membranes

-Associated with a positive Nikolsky’s sign- slight rubbing of the skin results in exfoliation of the outermost layer

44
Q

Describe Skin lesions- distribution

A
  • Localized: lesions or abnormality appears in one small area
  • Regional: lesions appear in a specific region of the body
  • Examples- flexor surfaces, extensor surfaces

-Generalized/disseminated- Lesions or abnormality appears widely distributed or in multiple areas simultaneously

45
Q

Describe the different characteristic distribution of skin lesions

A

Acne vulgaris: Face, chest, upper back
Atopic Dermatitis: Flexor surface (behind the knees/elbow crease)
Photosensitive eruptions: places exposed to the sun
Pitybiasis rosea: Tank top region and butt
Psoriasis: Knees and elbows
Seborrehic dermatitis: head

46
Q

Describe Round/discoid lesions

A
  • Coin shaped with no central clearing
  • Example- nummular eczema (a form of atopic dermatitis)
  • Umbilicated lesions
  • Example- seen with molluscum contagiosum
47
Q

Describe Oval/Ovoid lesions

A

-Example- Pityriasis rosea

48
Q

Describe Annular lesions

A
  • Round; active margins with central clearing

- Seen with tinea (fungal) infections

49
Q

Describe shape/arrangement of lesions

A
  • Dermatomal: Following a nerve segment (Herpes Zoster)
  • Linear
  • Serpiginous: Cutaneous larva migrans from hookworm larvae)
  • Morbilliform: Measles-like (Erythematous maculopapular lesions that become confluent on the face and body)
  • Target/targetoid: Pink macules with purple central papules (Erythema multiforme)
50
Q

Describe Skin borders/margins

A
  • Distinct: Well-demarcated or defined; able to draw a line around the area with confidence
  • Indistinct: Poorly defined; borders merge with normal skin
  • Active: Margin of lesion shows greater activity than center (Tinea infections)
  • Irregular: Margins are notched, not smooth (malignant melanoma)
  • Raised borders: Center of lesion is depressed compared to edge (Basal cell carcinoma)
51
Q

What are the ABCDEs of Melanoma?

A
A- Asymmetrical shape
B- Borders (irregular)
C- Color (variation)
D- Diameter (> 6mm, pencil eraser)
E- Evolving