Skin Flashcards
What disease is an example of hyperkeratotic parakeratosis?
Superficial Necrolytic dermatitis
What diseases are characterized by hyperkeratosis?
Ichthyosis
Superficial necrolytic dermatitis
Seborrhea
What disease is characterized by full thickness necrosis?
Toxic epidermal necrolysis
What lesions/signalment characterizes dyskeratosis/dysplasia/actinic dermatitis?
Distribution of non-healing lesions on flanks and underside
Sparsely haired, lightly pigmented dogs
What disease is characterized by necrosis of individual cells?
Erythema multiforme
What diseases are commonly drug-induced?
Erythema multiforme
Toxic epidermal necrolysis
Intercellular edema is called
Spongiosis
What type of intracellular fluid accumulation is often a viral cytopathic effect and what would you see on histopath?
Ballooning degeneration
Pale keratinoctes with intranuclear inclusions
What type of intracellular fluid accumulation is associated with autoimmune diseases?
Hydropic degeneration
What epidermal changes are associated with superficial necrolytic dermatitis?
Hyperplasia
Edema
Hyperkeratosis
What are factors that contribute to acantholysis?
Type 2 hypersensitivity
Ezymatic destruction
Pustule formation and acantholysis are commonly associated with what autoimmune disease?
Pemphigus foliaceous
What secondary lesions form from a primary pustule?
Crusts
What disease is an immune-mediated separation of epidermis and dermis?
Bollus pemphigoid
What are the primary and secondary lesions of bollus pemphigoid?
Primary- vesicle
Secondary- ulcer
Pautrier’s microabscesses are associated with what disease?
Mycosis fungoides
What is associated with hypopigmentation?
Damage to melanocytes or basement membrane
Defects in formation of melanin or lack of melanocytes
What is the difference between urticaria and angioedema?
Urticaria: compartmentalized collection of fluid in dermis, multiple areas
Angioedema: whole area of edema, not 1 discrete area
What disease is calcinosis cutis associated with?
Hyperadrenocorticism
What are the most common sites for calcinosis cutis?
Dorsal interscapular region
Inguinal region
Axillary region
What lesions occur in the subcutis?
Panniculitis
Fat necrosis
What is the most common type of dermatitis?
Perivascular
Eosinophils = hypersensitivity
What is a common cause of interface dermatitis?
Immune-mediated (cytotoxic T cells attack keratinocytes, melanocytes, or BM)
E.g. Discoid lupus
What is uveodermatologic syndrome (VKH)
Damage to melanocytes resulting in uveitis/photophobia and hypopigmentation
Vasculitis is caused by what type of hypersensitivity?
Type III
Subcorneal vesicles or pustules are associated with what diseases?
Superficial pyoderma
Pemphigus foliaceous
Suprabasilar vesicles or pustules are associated with what disease?
Pemphigus vulgairs
Subepidermal vesicles or pustules are associated with what disease?
Bullous pemphigoid SLE TEN Burns EB
What are the 3 most common causes of folliculitis/furunculosis?
Bacteria
Dermatophytes
Parasites (mites)
What disease presents as interface folliculitis?
Discoid lupus
Demodicosis
What is a common cause of panniculitis?
Atypical mycobacterium, nocardia
Commonly on abdominal fat pad of cats
What disease is associated with rabies vaccines?
Atrophic dermatoses
What is the most common cause of atrophic dermatoses?
Hormonal imbalance
