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Systemic Pathology Exam 2 > Skin > Flashcards

Skin Flashcards

1
Q

What disease is an example of hyperkeratotic parakeratosis?

A

Superficial Necrolytic dermatitis

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2
Q

What diseases are characterized by hyperkeratosis?

A

Ichthyosis
Superficial necrolytic dermatitis
Seborrhea

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3
Q

What disease is characterized by full thickness necrosis?

A

Toxic epidermal necrolysis

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4
Q

What lesions/signalment characterizes dyskeratosis/dysplasia/actinic dermatitis?

A

Distribution of non-healing lesions on flanks and underside

Sparsely haired, lightly pigmented dogs

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5
Q

What disease is characterized by necrosis of individual cells?

A

Erythema multiforme

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6
Q

What diseases are commonly drug-induced?

A

Erythema multiforme

Toxic epidermal necrolysis

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7
Q

Intercellular edema is called

A

Spongiosis

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8
Q

What type of intracellular fluid accumulation is often a viral cytopathic effect and what would you see on histopath?

A

Ballooning degeneration

Pale keratinoctes with intranuclear inclusions

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9
Q

What type of intracellular fluid accumulation is associated with autoimmune diseases?

A

Hydropic degeneration

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10
Q

What epidermal changes are associated with superficial necrolytic dermatitis?

A

Hyperplasia
Edema
Hyperkeratosis

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11
Q

What are factors that contribute to acantholysis?

A

Type 2 hypersensitivity

Ezymatic destruction

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12
Q

Pustule formation and acantholysis are commonly associated with what autoimmune disease?

A

Pemphigus foliaceous

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13
Q

What secondary lesions form from a primary pustule?

A

Crusts

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14
Q

What disease is an immune-mediated separation of epidermis and dermis?

A

Bollus pemphigoid

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15
Q

What are the primary and secondary lesions of bollus pemphigoid?

A

Primary- vesicle

Secondary- ulcer

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16
Q

Pautrier’s microabscesses are associated with what disease?

A

Mycosis fungoides

17
Q

What is associated with hypopigmentation?

A

Damage to melanocytes or basement membrane

Defects in formation of melanin or lack of melanocytes

18
Q

What is the difference between urticaria and angioedema?

A

Urticaria: compartmentalized collection of fluid in dermis, multiple areas

Angioedema: whole area of edema, not 1 discrete area

19
Q

What disease is calcinosis cutis associated with?

A

Hyperadrenocorticism

20
Q

What are the most common sites for calcinosis cutis?

A

Dorsal interscapular region
Inguinal region
Axillary region

21
Q

What lesions occur in the subcutis?

A

Panniculitis

Fat necrosis

22
Q

What is the most common type of dermatitis?

A

Perivascular

Eosinophils = hypersensitivity

23
Q

What is a common cause of interface dermatitis?

A

Immune-mediated (cytotoxic T cells attack keratinocytes, melanocytes, or BM)

E.g. Discoid lupus

24
Q

What is uveodermatologic syndrome (VKH)

A

Damage to melanocytes resulting in uveitis/photophobia and hypopigmentation

25
Q

Vasculitis is caused by what type of hypersensitivity?

A

Type III

26
Q

Subcorneal vesicles or pustules are associated with what diseases?

A

Superficial pyoderma

Pemphigus foliaceous

27
Q

Suprabasilar vesicles or pustules are associated with what disease?

A

Pemphigus vulgairs

28
Q

Subepidermal vesicles or pustules are associated with what disease?

A 
Bullous pemphigoid
SLE
TEN
Burns
EB
29
Q

What are the 3 most common causes of folliculitis/furunculosis?

A

Bacteria
Dermatophytes
Parasites (mites)

30
Q

What disease presents as interface folliculitis?

A

Discoid lupus

Demodicosis

31
Q

What is a common cause of panniculitis?

A

Atypical mycobacterium, nocardia

Commonly on abdominal fat pad of cats

32
Q

What disease is associated with rabies vaccines?

A

Atrophic dermatoses

33
Q

What is the most common cause of atrophic dermatoses?

A

Hormonal imbalance

Systemic Pathology Exam 2 (2 decks)

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