Lymph Flashcards

1
Q

B-cells in lymph nodes are normally located in which areas?

A

Follicles

Medullary chords

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2
Q

What cause lymph node atrophy?

A

Viruses (Distemper, parvovirus)
Glucocorticoids
Chemo/radiation
Malnutrition

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3
Q

What causes lymph node hyperplasia?

A

Ag stimulation

Viral (malignant catarrhal fever, bovine leukemia, FIV)

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4
Q

What causes lymph node hypoplasia?

A

Primary immunodeficiency (CID)

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5
Q

What causes lymph node enlargement?

A

Lymphadenitis
Neoplasia (Lymphoma)
Lymphoid hyperplasia

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6
Q

What causes uniform splenomegaly?

A

If bloody: congestion or torsion

If non-bloody:
Bacteremia/septicemia
Granulomatous splenitis
Hemolytic anemia
Lymphoma
Extramedullary hematopoiesis
Amyloidosis
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7
Q

What causes splenic nodules/masses?

A

If bloody: hematoma, hemangioma/sarcoma, Nodular hyperplasia with hyperemia, infarct, incomplete contraction

If non-bloody: Nodular hyperplasia, granulomatous splenitits, lymphoma, metastatic neoplasm

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8
Q

What diseases are associated with a large thymus?

A

Hemorrhage
Lymphoma
Thymoma (epithelial cells)

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9
Q

What diseases are associated with a small thymus?

A
Hypoplasia
Involution
Thymitis 
Atrophy 
Viral- FeLV, FIV, distempet, panleuk, parvo
Glucocorticoids
Nutritional deficiency
Toxins
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10
Q

What is the most common distribution of lymphoma in dogs?

A

Multicentric

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11
Q

What is the most common distribution of lymphoma in cats?

A

Ailmentary

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12
Q

How does thymic lymphoma present in cats?

A

Respiratory disease

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13
Q

What is the most common distribution of lymphoma in cattle?

A

Multicentric

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14
Q

Right atrial lymphoma is most common in what species?

A

Cattle

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15
Q

Spinal cord involvement with posterior paresis associated with lymphoma is common in what species?

A

Cattle

Down cow with no explanation

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16
Q

Viral agents have been associated with lymphoma in what species?

A

Dogs, cats, cattle

17
Q

What is the most common distribution of lymphoma in horses?

A

Multicentric

18
Q

What is the WHO classification of canine lymphoma?

A

B-cell neoplasms

T-cell and NK-cell neoplasms

19
Q

What enzyme is deficient in Arabian foals with CID?

A

DNA-dependent protein kinase