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Pharm > Skin * > Flashcards

Skin * Flashcards

1
Q

Brimonidine (mirvaso)

A

uses rosacea
MOA- alpha adenoreceptor agonist reduces edema through vasoconstriction
Gel
ADE- burning, warm feeling, flushing

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2
Q

Doxycycline (oracea)

A

Uses rosacea
MOA- tetracycline antibiotic, anti inflammatory
Capsule/tablet
ADE- diarrhea, nausea, dyspepsia, nasopharyngitis

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3
Q

Ivermectin

A

Rosacea
Anti parasitic agent
Unknown MOA- antiinflammatory, kill skin mites
Cream
ADE- irritation, burning

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4
Q

Metronidazole (metrogel)

A

For rosacea
Antiinflammatory/immune suppression
Cream/gel/lotion
ADE- burning, erythema, irritation, xeroxerma, acne

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5
Q

Minocycline (zilxi)

A

For rosacea
Local anti inflammatory

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6
Q

Oxymetazoline (rhofade)

A

For rosacea
MOA- alpha receptor agonist reduces erythema through vasoconstriction
ADE- dermatitis, worsening inflammatory lesions, itching; erythema, burning

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7
Q

Corticosteroids

A

Uses- psoriasis, many others
MOA- antiflammatory, anti proliferative, immunosuppressant, vasoconstriction
ADE- skin atrophy, striae, acne, dermatitis, local infections, hypopigmentation

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8
Q

Antibiotics for acne

A

Drugs- clindamycin (cleocin), erythromycin, minocycline, doxycycline
Uses- moderate to severe acne
Foam/gel/lotion/oral
DC once lesions clear, and continue maintenance therapy like retinoids/benzoyl peroxide

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9
Q

Azelaic acid (azalex)

A

Uses- acne, rosacea
MOA- antibiotic activity against c. Acne, inhibit protein synthesis, antiinflammatory
Can cause lightening to skin
Cream/gel
ADE- mild, transient itching, burning, stinging, tingling

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10
Q

Benzoyl peroxide

A

Uses- acne 1st line for mild to moderate
MOA- bacterialcidal for c. Acnes, reduced inflammation, comedolytic activity
Topical/washes/foams/cream/gel
ADE- dry skin, irritation, bleaching of cloth, contact dermatitis

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11
Q

Dapsone (aczone)

A

Uses- acne
MOA- anti inflammatory, anti bacterial, interfere with neutrophilic function and tumor necrosis factor alpha
Topical/gel
ADE- oiliness, dryness, erythema

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12
Q

Bacitracin

A

Uses-acne
Class- Peptide antibiotic
Often used in combo with neomycin/polymyxin to prevent infection of wounds
Topical/ointment
systemic toxic

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13
Q

Gentamycin

A

Class- aminoglycoside
MOA- interferes with protein synthesis, for gram - organisms
Often used in combo with cream/ointment

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14
Q

Mupirocin

A

Uses- acne, prevention of NI in hospital, impetigo, MRSA
MOA- inhibit protein synthesis for gram + organism
Cream/ointment/nasal
ADE- itching, skin rash, burning

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15
Q

Neomycin

A

uses-acne
MOA- interferes with bacterial protein synthesis: gram - bacteria, some gram +
Often in combo with bacitracin or polymyxin ointment
ADE- contact dermatitis, erythema, rash, itching, hives

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16
Q

Ozenxacin

A

MOA- quinolone, inhibits DNA replication, kills staph and strep, MRSA
Uses- impetigo in those 2 months or older
ADE- itching, redness, dryness

17
Q

Polymyxin

A

Class- cyclic hydrophobic peptide
MOA- disrupts bacterial cell wall in gram - organism
Used in combo with bacitracin, neomycin
Uses- prevent skin infection

18
Q

Retapamulin (altabax)

A

MOA protein synthesis inhibitor for gram + bacteria
Uses- impetigo
Ointment
ADE- itching, irritation

19
Q

Retinoids

A

Drugs- tazarotene (tazorac), trentinoin (rentin A), adalapene (differin)
Uses- acne, psoriasis, severe rosacea
MOA- vitamin A derivative that interacts with retinoid receptors to regulate gene expression to normalize retinocyte differentiation, proliferation, and reduce sebum production, anti inflammatory
ADE- erythema. Peeling, burning, stinging, dry MM. photosensitive
Avoid in pregnancy especially topical
Isotrentinoin (accutane) category X

20
Q

Salicylic acid

A

MOA- penetrates pilosebaceous units and works as exfoliant anti inflammatory
Uses- mild acne
OTC facial washes/pads
ADE- skin peeling, dryness, local irritation

21
Q

Sulfacetimide sodium

A

MOA - interferes with bacterial growth in combo with sulfur
Uses- inflammatory acne lesions
Cleanser/cream/foam/gel/lotion/pads/suspension/wash
ADE- contact dermatitis, erythema, itching, dryness

22
Q

Actinic keratosis

A

Dry scaly lesions occurring on sun exposed areas precursor to SCC
Therapies- efudex (5flourouracil), aldara (lmiquimod), cryotherapy, currttage,

23
Q

Atopic dermatitis

A

Treated with emollients and topical steroids and maybe immune modulators

Pharm (16 decks)

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