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PHARM 233 (Drugs) > Skin > Flashcards

Skin Flashcards

1
Q

Hydrocortisone

A

Glucocorticoid
- Mild

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2
Q

Alclomethasone Diproprionate

A

Glucocorticoid
- Moderate

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3
Q

Beclomethasone Diproprionate

A

Glucocorticoid
- Potent

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4
Q

Clobetasol Proprionate

A

Glucocorticoid
- Very Potent

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5
Q

Tretinoin

A

Retinoid
- Derivative of Vitamin A Metabolites

Reduce sebaceous gland activity
Reduce sebum production

Treats:
- Acne
- Eczema
- Psoriasis

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6
Q

Isotretinoin

A

Retinoid
- Derivative of Vitamin A Metabolites

Reduce sebaceous gland activity
Reduce sebum production

Treats:
- Acne
- Eczema
- Psoriasis

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7
Q

Alitretinoin

A

Retinoid
- Derivative of Vitamin A Metabolites

Reduce sebaceous gland activity
Reduce sebum production

Treats:
- Acne
- Eczema
- Psoriasis

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8
Q

Tazarotene

A

Retinoid
- Derivative of Vitamin A Metabolites

Reduce sebaceous gland activity
Reduce sebum production

Treats:
- Acne
- Eczema
- Psoriasis

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9
Q

Bexarotene

A

Retinoid
- Derivative of Vitamin A Metabolites

Blocks Cell Cycle Progression
- Treats Cutaneous T-Cell Lymphoma

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10
Q

Calcitriol

A

Vitamin D Analogue

Treats:
- Psoriasis

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11
Q

Calcipotriol

A

Vitamin D Analogue

Treats:
- Psoriasis

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12
Q

Tacalcitol

A

Vitamin D Analogue

Treats:
- Psoriasisv

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13
Q

Salicylic Acid

A

Keratolytic (a-hydroxy acids)

Treats:
- Warts

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14
Q

Glycolic Acid

A

Keratolytic (a-hydroxy acids)

Treats:
- Warts

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15
Q

Cryotherapy

A

Treats:
- Warts

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16
Q

Imiquimod

A

Immune Modifier
- Treats Warts

17
Q

Cyclosporine

A

Immunosuppressant (Cyclic Peptide)

Inhibits Calcineurin
–> Decrease IL-2 Synthesis
–> Decrease Proliferation of T-Cell

Treats:
- Serious Eczema
- Serious Psoriasis

18
Q

Tacrolimus

A

Immunosuppressant (Macrolide)

Inhibits Calcineurin
–> Decrease IL-2 Synthesis
–> Decrease Proliferation of T-Cell

Treats:
- Serious Eczema
- Serious Psoriasis

Adverse Effect:
- Alopecia

19
Q

Pimecrolimus

A

Immunosuppressant (Macrolide)

Inhibits Calcineurin
–> Decrease IL-2 Synthesis
–> Decrease Proliferation of T-Cell

Treats:
- Serious Eczema
- Serious Psoriasis

20
Q

TNFa

A

Pro-Inflammatory Interleukins

21
Q

IL-1a/B

A

Pro-Inflammatory Interleukins

22
Q

IL-4, IL-10, IL-13

A

Anti-Inflammatory Interleukins

23
Q

MCP-1

A

Chemokines (C-C)

24
Q

RANTES

A

Chemokines (C-C)

25
Q

CXCL-12

A

Chemokines (C-X-C)

26
Q

IFNa

A

Interferons
- Treats Chronic Hepatitis B & C
- Treats malignant disease

27
Q

IFNb

A

Interferons
- Treats Relapsing Multiple Sclerosis

28
Q

IFN(gamma)

A

Interferons
- Reduces infection in immunodeficiency disease (Chronic Granulomatous Disease)

29
Q

Cytokines and Growth Factors

A

Colony Stimulating Factors

30
Q

Infliximab

A

Chimeric Neutralizing Antibody
- Targets TNFa

Treats Psoriasis

31
Q

Adalimumab

A

Humanized Monoclonal Antibody
- Targets TNFa

Treats Psoriasis

32
Q

Secukinumab

A

Monoclonal Antibody
- Targets IL-17

Newer Treatment for Psoriasis

33
Q

Ixekizumab

A

Monoclonal Antibody
- Targets Homodimers of IL-17A

Newer Treatment for Psoriasis

34
Q

Ustekinumab

A

Monoclonal Antibody
- Targets IL-12 and IL-23

Newer Treatment for Psoriasis

PHARM 233 (Drugs) (6 decks)

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