skim first aid Flashcards
IgA protease bacteria
SHiN: S pneumo, H influ Type B, Nesisseria
Type III secretion system bacteria
Psuedomonas, shigella, salmonella, e coli
Protein A, M protein
Protein A is Staph (prevent opsonization and phagocytosis by binding Fc region of IgG), M protein is GAS (helps prevent phagocytosis, cause of rheumatic fever)
Colon cancer subacute endocarditis/bactermia bacteria
S. Bovis
Bacteria polypeptide capsule
(D- glutamate capsule), B anthrax
Alpha Toxin bacteria
C perfringens (it is a lecithinase, phospholiapse) that give gas gangrene properites
C Diff Toxins
Toxin A: enterotoxin; brush broder, alter fluids
Toxin B: Cytotoxin, disrupts acitn polymerization and cyotksleton (causes pseudomembrane)
Rocket tails and actin polymerization
Listeria (tx with ampicillin)
Nocardia properties
Aerobe, acid fast, found in soil, causes pulm infections or cutaneous infections ni immunocomp; can spread to CNS. Tx with TMP-SMX
Cord Factor bacteria and sulfatides
Mycobacter; esp in vvirulent TB strains. Activates macrophages, induce release of TNF alpha.
sulfatides inhibit phagolysosomal fusion
tx for tuberculoid leprosy vs leprometous form, immune response differences
lepromatous: tx with dapsone, rifampin and CLOFAZAMINE. Mostly a humoral Th2 response with low cell mediatedi mmunity
Tuberculoid:: few hairless skin plaques; high cell mediated immunity, mostly Th1 tx with dapsone and rifampin only
What is Fitz Hugh Curtis Syndrome
complication of N. Gonnorhea where it expands to the peritoneum I believe
Dosing time H influ B vaccine, tx
2-18 months, tx amox/clav for mucosal, ceftriaxone for meningitis and systemic, rifampin for close contacts
Rapid dx of legionella
urine antigen
Strain of E coli for invasive diarrhea?
EIEC
Feature (bresides HUS) for EHEC to distinc from other e coli
Does not ferment sorbitol
What is in vaccine for S Typhi, disease casued
capsule polysaccharide
typhoid fever: rose spots on abdomen, constipation, abdominal pain, fever, can be hornic carrier in gall bladder
cause of psuedoappendicitis
yersine enterocolitica (ram negative, pet feces, contam pork/milk)
H Pylori tx
amox (or metron if penicillin allergy), Clarithromyicn, PPI
Spirochetes
Borrellia, leptospira, treponema
Leptospira interrogans
spirochete, hook shaped guys, Weil disesase: jaundice and azotemia from liver, kidney dysfunc, feve,r hemorrhage
Sx congenital syphilis
rhagades (linear scars at angle of mouth), mulberry mollars, saber shins, CNVII deafness, snuffles (nasal discharge), saddle nose. Treat mom asap to prevent
cause of Jarish-Herxheimer
killing syphilis->flu like syndrome due to increased LPS and cytokines frmo lysed cells
chlamydia A-C, D-K L1 and L2 L3 differences
ABC is the blidnes sand follic conjunctiivits in africa
D-K is your STD and PID guy (also neonatal pnemonia with eosinophilia), neonatal conjunc (1-2 weeks after birth later than n gonn, get in birth ganal0
L1,L2,L# is thesmall painless ulcers on genitals->swollen painfl lymph nodes
tx with doxy
key test and agar for M pneumonia
cold aggltinoaton (IgM) Eaton agar
Captains wheel fungi
paracoccidiomycosis (altin america, very large)
cause of oncomycosi
tinea unguinum
cause of tinea versiciolor
malessia spp (spaghetti and meatballs apperance on microscopy). Degrade lipids->make acids-> damage melanocytes.
Tx selenium sulfide
pseudohyphae 20c, germ tube at 37
candida
septate hyphae at 45 degree angle
aspergillus
narrow budding, heavily encapsulated, not dimorphic
cryptococcus
irregular, broad, nonseptate, WIDE angles
mucor and rhizopus