SkelRad A Midterm Flashcards
What germ layer is bone derived from?
mesoderm
Diaphysis
primary center of ossification
epiphysis
secondary center of ossification
apophysis
secondary growth centers
a protuberance
functions as the attachment site for ligaments and tendons
Enthesis
site of attachment of tendons and ligaments
highly vascularized
high metabolic activity
What are the four functions of periosteum
attaches to the cortex via sharpey’s fibers
maintains caliber of bone by appositional bone growth
provies a transitional zone of attachment for muscles, ligament, and tendons
serves as a source of vascular perfusion for the outer third of the cortex
5 zones of the growth plate:
metaphysis zone of degeneration zone of hypertrophy zone of proliferation resting cartilage
Resting cartilage
attaches growth plate to epiphysis
if injured, growth stops
zone of proliferation
where bone is lengthened due to active growth of chondrocytes
if cells die, growth stops
zone of hypertrophy
chondrocytes mature
no active growth
weakest portion of the plate
site of salter-harris fractures
zone of degeneration
aka zone of ossification
site of dying chrondrocytes, ossification starting
attaches growth plate to metaphysis
What type of bone marrow is hematopoietically active
Red marrow
what type of bone marrow increases with age
yellow (fatty) marrow
how are calcium and phosphorous levels related?
inversely
what are the two main functions of parathormone
stimulate and control the rate of bone remodeling
influence mechanisms governing control of plasma level calcium
Two direct effects of parathormone
stimulates ca++ absorption from glomerular fluid in kidneys
promotes osteoclastic resorption in the bone
indirect effect of parathormone
influences rate of calcium absorption in the intestine
functions of vitamin d
regulates intestinal mineral absorption
maintains skeletal growth and mineralization
Vitamin D
key hormone responsible for calcium absorption from the diet
Categories of bone disease
"cat bites" congenital arthritis trauma blood (hematological) infection tumor endocrine, nutritional, metabolism soft tissue
Types of osteolytic lesions
geographic
motheaten
permeative