Skeletal v. Cardiac v. Smooth Muscle Mechanisms Flashcards
1
Q
Curare
A
- Block nicotinic ACh channels by competing for ACh binding site
2
Q
Botulism
A
decrease release of Ach from axon terminals
3
Q
methacholine, carbachol, nicotine
A
- bind and activate nicotinic ACh receptors
* not destroyed by AChE - prolonged effect (reason they are stimulant)
4
Q
neostigmine, physostigmine, diisopropyl fluorophosphate or ‘nerve gas’
A
- block the degradation of ACh by inactivating acetycholinesterase in the synapse
- prolong its effect
5
Q
Epinephrine
A
relaxation of gut
constriction of blood vessels
6
Q
CCK
A
contraction of bladder
7
Q
Ang. II, ADH
A
constriction of blood vessels
8
Q
Histamine
A
gastric contraction
9
Q
EC K, NO, CO2, adenosine
A
relaxation of blood vessels
