Skeletal System/Bones Flashcards
Endochondral Ossification step 1
Chondrocytes at the center of of the growing cartilage model enlarge and then die as the matrix calcifies.
Endochondral Ossification step 2
Newly derived osteoblasts cover the shaft of the cartilage in a thin layer of bone.
Endochondral Ossification step 3
Blood vessels penetrate the cartilage. New osteoblasts form a primary ossification center.
Endochondral Ossification step 4
The bone of the shaft thickens and the cartilage near each epiphysis is replaced by shafts of bone.
Endochondral Ossification step 5
Blood vessels invade the epiphyses and osteoblasts from secondary centers of ossification. (fully formed bone @ this stage)
Endochondral Ossification
Hyaline cartilage model replaced by bone
Most bones formed this way
Intramembranous Ossification
Bone develops from s fibrous connective tissue membrane
Forms flat bones of skull, mandible, clavicle, sternum
Osteoblasts
Bone forming cells
Osteoclasts
Bone destroying cells
Osteoprogenitor cells
Precursors to osteoblasts
Osteocytes
Mature bone cells (osteoblasts) trapped in lacuna between lamellae