Skeletal muscle relaxant drugs Flashcards
1
Q
atracurium cisatracurium mivacurium d-tubocurarine pancuronium pipercuronium rocuronium vecuronium
A
- nondepolarizing blocker of the NMJ
- prevents access of ACh to its receptor
- risk of bronchospasm
2
Q
succinylcholine
A
- depolarizing blocker of NMJ
- activates ACh receptor and keeps channel open
- very short acting
3
Q
ambenzonium donepezil echothiophate edrophonium galantamine neostigmine physostigmine pyridostigmine rivastigmine tacrine
A
- AChE inhibitor
- used for myasthenia gravis, dementia
4
Q
atropine
glycopyrrolate
A
Anti-muscarinic
5
Q
d
A
d
6
Q
baclofen
A
- GABAb blocker
- spasmolytic drug
- results in inhibition of excitatory neurotransmitter release
7
Q
carisprodol
A
-spasmolytic, anxiolytic
8
Q
cyclobenzaprine
A
-spasmolytic, drowsiness
9
Q
diazepam
A
- GABAa receptor agonist
- spasmolytic drug
- increases effect of GABA on its receptor
10
Q
tizanidine
A
-spasmolytic drug
11
Q
botox
A
- cleaves the VAMP and blocks vesicle fusion to presynaptic membrane
- spasmolytic agent
12
Q
glucocorticoids
A
- MS treatment
- immunosuppressive
13
Q
glatiramer acetate
A
- MS treatment
- activate T lymphocyte suppressor cells
14
Q
IFN-β
A
- MS treatment
- inhibit T lymphocyte adhesion to BBB
15
Q
mitoxantrone
A
- MS treatment
- antineoplastic
- intercalates into DNA and causes strand breaks and cross links
