Skeletal 3 Flashcards
Matrix
Osteoid – organic material secreted by osteoblasts
Collagen (fiber), Proteoglycans & Glycoproteins (ground substance)
Provides flexibility so inadequate fiber leads to brittle bones
Calcification
Inorganic salts
Hydroxyapatite (Ca10(PO4)6(OH)2) & ions crystalize & deposit around collagen
Hardens bone so inadequate Ca+2 leads to soft bones
connective tissues, cartilage & bone are formed by
blast cells that secrete matrix & mature into -cyte cells
Chondrin
is the matrix of cartilage
Osteoid
is the matrix of bone.
Cartilage growth
is formed by chondroblasts secreting chondrin. Trapped chondroblasts mature into chondrocytes.Cartilage lacks blood vessels & calcification
Bone growth
is formed by osteoblasts that secrete osteoid. The osteoid is then calcified, & the trapped osteoblasts mature into osteocytes. Initial bone growth produces spongy & compact bone & when appropriate medullary cavities. Bone has both. blood vessels & calcification
Endochondrial
within cartilage
Appositional
on the surface (perichondrial, periosteal, endosteal…)
Interstitial =
between cells, within spaces of organs or tissues, not in body cavities
Cartilage growth
this interstitial growth is within mesenchyme)
Cartilage Growth – Maintenance & Remodeling
Interstitial or Appositional)