Sjogren Syndrome

Question 1

What is Sjogren syndrome?

Answer 1

An autoimmune disorder characterised by reduced secretion from the lacrimal and salivary glands, leading to dry eyes and mouth

Question 2

Sjogren’s syndrome Sx

Answer 2

1. Dry/gritty eyes
2. Dry mouth
3. Dry vagina
4. Raynaud’s phenomenon

Question 3

Specific Auto antibodies to Sjogren’s

Answer 3

Anti-Ro/Anti-La

Question 4

2 for eyes, 2 for mouth

Special tests to Sjogren’s

Answer 4

1. Schirmer’s test: test for reduced tear production
2. Rose Bengal staining of the cornea: For keratitis due to conjuctivitis sicca
3. Salivary Flow rate monitoring:
4. Salivary Gland Bx