Sjogren's

Question 1

What is Sjogren’s?

Answer 1

Autoimmune condition affecting exocrine glands, leading to dry mucous membranes

Question 2

Who is Sjogren’s seen in?

Answer 2

F>M

Onset 40-50

Question 3

What is the presentation of Sjogren’s?

Answer 3

Dry eyes, mouth, vagina
Parotid gland enlargement
Systemic= fatigue, fever, myalgia, arthralgia
5-10%= organ involvement

Question 4

What investigations are done for Sjogren’s?

Answer 4

Autoantibodies= Ro, La

Schirmer test

Question 5

What is the Schirmer test?

Answer 5

Fulter paper under eyelid and assess how far tears travel

Question 6

What is the management of Sjogren’s?

Answer 6

Artificial tears and saliva
Vaginal lubrication
Immunosuppression= hydroxychloroquine

Question 7

What are the common complications of Sjogren’s?

Answer 7

Conjunctivitis, corneal ulcers
Dental cavities and candida infections
Sexual dysfunction

Question 8

What are the more rare and severe complications of Sjogren’s?

Answer 8

Lymphoma
Purpura
Interstitial lung disease
Renal tubular necrosis