SJIA, HLH, MAS Flashcards
Most common type of chronic rheumatic disease of childhood; onset <16 years, one more more joints (swelling, effusion, limited ROM, etc.) and exclude any other form; due to genetic predisposition, environmental triggers and disordered immune response
Juvenile Idiopathic Arthritis
Diagnostic Criteria for Juvenile Idiopathic Arthritis
Onset <16 yo
Arthritis one or more joints >6 weeks (Swelling, effusion, limited ROM, etc.)
Exclude other arthritis or disorders
Lab values for Juvenile Idiopathic Arthritis
NO SPECIFIC LAB VALUES
Inc. WBCs
Mild normocytic anemia
Inc. ESR/CRP
Subtypes of Juvenile Idiopathic Arthritis (6 total)
Oligoarthritis (<4 joints) Polyarthritis (RF-) Polyarhtritis (RF+) Enthesitis-related Arthritis Psoriatic Arthritis Systemic Arthritis
Subtype of Juvenile Idiopathic Arthritis; <4 joints; MAJORITY of JIA; peaks between 1 and 2 years old; FEMALES; affects lower extremities; GOOD prognosis
Oligoarticular
Oligoarticular arthritis involves (males/females) and the (upper/lower) extremities with a (good/poor) prognosis
Females; Lower; Good
Most common subtype of Juvenile Idiopathic Arthritis
Oligoarthritis (<4 joints)
Eye finding that is commonly found with HLA-B27 arthritis (Oligoarthritis, Psoriatic, etc.)
Uveitis
RF (positive/negative) Polyarthritis is most common
RF-negative
Antibody associated with many types of arthritis; IgM antibody against the Fc portion of IgG
Rheumatoid Factor
Antibody that is more SPECIFIC for Rheumatoid Arthritis; against cyclic citrullinated proteins; predictor of more PROGRESSIVE disease
Citrullinated Protein Antibody
(RF/Anti-CCP) is more specific for Rheumatoid Arthritis
Anti-CCP (a few different arthritis have RF)
Subtype of Juvenile Idiopathic Arthritis; seen more commonly in MALES; inflammation of tendons/ligaments, resulting in Sacroiliac tenderness, uveitis and HLV-B27
Enthesitis-Related Arthritis
Subtype of Juvenile Idiopathic Arthritis is more common in males
Enthesitis-Related Arthritis
Subtype of Juvenile Idiopathic Arthritis; associated with dermatologic findings, such as dactylitis, nail pitting, onycholysis and Psoriasis
Juvenile Psoriatic Arthritis