SIR JED PART 3 Flashcards
NOT VALUABLE DETECTOR OF EARLY RENAL DISEASE BUT IS USED TO KNOW THE EXTENT OF NEPHRON. DAMAGE OF KNOWN CAUSE OF RENAL DAMAGE
GLOMERULAR FILTRATION TESTS
GENERALLY CONSIDERED THE BEST OVERALL INDICATOR OF THE LVEL OF KIDNEY FUNCTION
GLOMERULAR FILTRATION RATE
THE STANDARD TEST USED TO MEASURE THE FILTERING CAPACITY OF THE GLOMERULI
CLEARANCE TEST
MEASURE THE RATE AT WHICH THE KIDNEYS ARE ABLE TO REMOVE A FILTRABLE SUBSTANCE FROM THE BLOOD
CLEARANCEE TEST
NOT REABSORBED NOR SECRETED BY THE TUBULES. GOLD STANDARD
INULIN CLEARANCE
VALUABLE TO MEASURE VIABILITY OF TRANSPLANT KIDNEY
RADIONUCLEOTIDES
OLD— FILTEREDD , REABSORBED EARLIEST GLOMERULAR FILTRATION RATE
UREA
SMALL PROTEIN PRODUCED BY ALL NUCLEATED CELLS FILTERED THEN REABSORBED AND BROKEN DOWN BY RTE
CYSTATIN C
GLUCOCORTICOIDS ______ PRODUCTION OF CYSTATIN C
REDUCED
FROM HLA AND REMOVED FROM PLASMA BY FILTRATION
MORE SENSITIVE INDICATOR OF A DECREASE IN GFR THAN CREATININE CLEARANCE
BETA 2 MICROGLOBULIN
HIGH CREATININE CLEARANCE IN BLOOD
GLOMERULAR
HIGH CREATININE CLEARANCE IN URINE=
TUBULAR
FOR RENAL INTEGRITY
BETA 2 MICROGLOBUIN
MOST COMMONLY USED
FOUND AT A RELATIVE CONSTANT LEVEL IN THE BLOOD
CREATININE
GENTAMICIN, CEPHALOSPORINS,AND CIMETIDINE WHICH INHIBIT _____
CREATININE GO TO GLOMERULAR
CREATININE CLEARANCE IS BASED ON ______
JAFFE REACTION
NV FOR CREATININE CLEARANCE MALEE
107-139ML/MIN
NV OF CREATININE CLEARANCE FOR FEMALE
87-107 ML/MIN
VALUES ARE CONSIDERABLY _____ IN OLDER PEOPLE
LOWER
FORMULA IN CREATININE CLEARANCE
UV/P X 1.73/A
THIS TEST IS NOT RELIABLE FOR PX WHO HAS IMMUNE DISORDERS
BETA 2 MICROGLOBULIN
WHAT ARE THE VARIABLES IN COCKGROFT GAULT GFR FORMULA?
AGE, SEX, BODY WEIGHT IN KILOGRAMS
WHAT ARE THE VARIABLES IN MDRD?
AGE SEX RACE
MDRD IDMS IS MOST ACCURATE WHEN RESULTS ARE ____
LOWER THAN 60ML/MIN
NEWER METHOD DO NOT REQUIRE THE COLLECTION OF TIME URINE SPECIMEN USING JUST SERUM CREATININE, CYSTATIN C OR BETA 2 MICROGLOBULIN VALUES
ESTIMATED GLOMERULAR FILTRATION RATE (eGFR)
USED FOR ROUTINELY SCREENING PX AS PART OF A METABOLIC PROFILE AND ALSO TO MONITOR PATIENTS ALREADY DIAGNOSED WITH RENAL DISEASE OR AT RISK FOR RENAL DISEASE
eGFR
LOW MOLECULAR WEIGHT GLYCOPROTEIN THAT FUNCTION AS PROTAGLYDIN D SYNTHASE
BETA TRACE PROTEIN
MARKER FOR CSF LEAKAGE
OTORRHEA
RHINORRHEA
FILTERED AT THE GLOMERULUS FREELY AND NOT REABSROBED
TRYPTOPHAN GLYCOCONJUGATE
WHAT METHOD IS. USED TO DETECT TRYOTOPHAN GLYCOCONJUGATE ?
HPLC
THIS TEST IS NOT RECOMMENDED FOR TRANSPLANT PX
CYSTATIN C
tubules are both
reabsorption and secretion of substance