sintesis de colesterol Flashcards

1
Q

Acetil-CoA

A

Tiolasa—>AcetoAcetil-CoA

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2
Q

AcetoAcetil-CoA

A

HMG-CoA sintasa–>HMG-CoA

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3
Q

β-Hidroxi-β-metilglutaril-CoA

A

HMG-CoA Reductasa—>Mevolonato

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4
Q

Mevolonato

A

Mevolonato-5-P-transferasa–>5-P-mevolonato

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5
Q

5-P-mevolonato

A

Fosfomevolonato Kinasa–>5-PP-mevolonato

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6
Q

5-PP-mevolonato

A

PP-mevolonato descarboxilasa—>3-5-PP-mevolonato

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7
Q

3-p-5-PP-mevolonato

A

PPi-mevolonato descarboxilasa–>Isoprenos: Isopentenyl ppi y dimetil PPi

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8
Q

Isoprenos: Isopentenyl pirofosfato y dimetil PPi

A

prenil transferasa—>Geranil PPi

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9
Q

Geranil PPi

A

prenil transferasa—->Farneasyl PPi

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10
Q

Farneasyl PPi

A

squaleno sintasa—>squaleno

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11
Q

squaleno

A

escualeno monoxigenasa–>escualeno 2,3 epoxi

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12
Q

escualeno 2,3 epoxi

A

2,3 Oxidoescualeno lanosterol ciclasa—->lanosterol

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13
Q

lanosterol

A

via insaturada(boch) , vía saturada(kandustch rusell)

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