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INT - Endócrino > Síndrome de Cushing > Flashcards

Síndrome de Cushing Flashcards

1
Q

Definição

A

Exposição prolongada a glicocorticoide (hipercortisolismo)

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2
Q

Causas endógenas

A

ACTH dependente ou independente

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3
Q

Causas exógenas

A

Corticoides

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4
Q

ACTH independente

A

ACTH baixo
Cortisol alto

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5
Q

ACTH dependente

A

ACTH alto
Cortisol alto

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6
Q

Doença de Cushing

A

Corticotropinoma (hipersecreção de ACTH)
ACTH dependente

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7
Q

ACTH independente

A

Adenomas (tumores benignos de adrenal)

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8
Q

Clínica

A

Hipertensão
Edema
Hipocalemia
Eventos tromboembólicos
Disfunção psiquiátrica
Hirsutismo
Obesidade central
Fadiga
Alopécia
Osteoporose
Doença cardiovascular
Dislipidemia
DM
Miopatia

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9
Q

Dx

A

Confirmar hipercortisolismo (salivar, sérico noturno, cortisol pós-dexametasonam urinário de 24h(

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INT - Endócrino (4 decks)

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