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farmaci sinapsi > Sinapsi 5HT > Flashcards

Sinapsi 5HT Flashcards

1
Q

ONDANSETRON

A

antiemetico

antagonista 5HT3

(non è attivo in CHINETOSI)

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2
Q

antiemetici

A

ONDASETRON

DOMPERIDONE

METACLOPRAMIDE

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3
Q

DOMPERIDONE

A

antiemetico
antagonista D2
no BEE

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4
Q

METACLOPRAMIDE

A

antiemetico

antagonista D2
antagonista 5HT3
agonista 5HT4 (motilità gastro-intestinale)

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5
Q

Triptani

A

Sumatriptan (agonista 5HT1D)

cefalea

non è selettivo

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6
Q

SUMATRIPTAN

A

agonsita non selettivo 5HT1D

cefalea

vasocostrizione vasi intracranici

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7
Q

BUSPIRONE

A

agonista parziale 5HT1A (ansia)

aumento appetito

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8
Q

aggregazione piastrinica

A

recettore 5HT2A

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9
Q

antagonista 5HT2A

A

antipsicotico atipico

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10
Q

TRIPTOFANO

A

amminoacido precursore iniziale di SEROTONINA

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11
Q

triptofano idrossilasi

A

triptofano —> 5-idrossitriptofano

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12
Q

5-idrossitriptamina

A

ammina

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13
Q

immagazzinamento-rilascio 5HT2A

A

cellule enterocromaffini

piastrine

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14
Q

recettore 5HT3

A

recettore canale cationico

riflesso del vomito

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15
Q

recettore 5HT1

A

Gq-Gi

vasocostrizione - vasodilatazione

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16
Q

recettore 5HT4

A

Gs

motilità gastro-intestinale

17
Q

recettore 5HT2

A

Gs

aggregazione piastrinica

18
Q

antidepressivi

A

inibizione re-uptake 5HT

19
Q

usi farmaci

A

ansiolitici

anti-emicrania

antidepressivi (inibizione re-uptake)

antiemetici

antipsicotici atipici

farmaci sinapsi (5 decks)

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