Sildenafil Flashcards

1
Q

Virkningsmekanisme

A

cGMP stiger via 2 funktioner:

  1. PDE5 inhiberes
  2. Stimulere NO til at binde til guanylat receptorer
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2
Q

Effekt

A

Vasodilatation primært i:

  • Lungevæv
  • Erektilt væv
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3
Q

Indikationer

A

Pulmonal hypertensions (fx ved hjertelungeorm)

Impotens (viagra)

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