Digoxin Flashcards

1
Q

Virkningsmekanismer

A

Hjerteglykosider –> inhibere Na/K-pumpe –> Na konc. stiger i cellen –> inducerer Na/Ca-pumpe –> Ca ind i cellen

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2
Q

Effekt

A
Negativ kronotrop (hjertefrekvens falder)
Positiv inotrop (stærkere myokardiekontraktion)
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3
Q

Indikationer

A

Takykardi ved hjerteinsufficiens

Atrieflimmer og atriflagren

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4
Q

Kontraindikationer

A

HCM

Subaortal- og pulmonal stenoser

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5
Q

Antidot

A

Øget K+ nedsætter digoxins toksititet

Øget Ca øger digoxins toksititet

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