SIHD & Angina 2 Flashcards

1
Q

Describe the process of arterial grafting in coronary artery bypass surgery.

A

Arterial grafting involves taking a healthy artery, like the left internal mammary artery (LIMA), and attaching it to the coronary artery downstream from a blockage to improve blood flow.

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2
Q

What is the advantage of using an arterial graft, such as LIMA, in bypass surgery?

A

Arterial grafts, like LIMA, are more durable and less prone to atherosclerosis compared to vein grafts, potentially lasting a lifetime.

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3
Q

Define the term ‘free graft’ in the context of coronary artery bypass surgery.

A

A free graft refers to a graft taken from a healthy artery, like the aorta, and attached downstream to bypass a blockage in a coronary artery.

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4
Q

How does the structure of veins differ from arteries in the context of grafting for bypass surgery?

A

Veins have a different structure and pressure differential compared to arteries, making them less ideal for long-term grafting as they are more prone to deterioration.

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5
Q

Describe the role of the left internal mammary artery (LIMA) in arterial grafting for coronary artery bypass surgery.

A

LIMA is often used as an arterial graft in bypass surgery, as it is durable, less prone to atherosclerosis, and can significantly improve symptoms for patients.

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6
Q

Describe the therapeutic options mentioned for patients with coronary artery disease.

A

Therapeutic options include medical therapy like statins, antiplatelets, and beta blockers, as well as coronary revascularization procedures like percutaneous coronary intervention and coronary artery bypass grafting.

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7
Q

What are some examples of disease-modifying therapies discussed in the content?

A

Examples of disease-modifying therapies include statins, antiplatelets, antianginals, beta blockers, and calcium antagonists.

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8
Q

How is coronary revascularization used in managing patients with coronary artery disease?

A

Coronary revascularization procedures like percutaneous coronary intervention and coronary artery bypass grafting are used to minimize symptoms and improve outcomes in patients with severe disease.

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9
Q

Define stable angina and its key characteristics as mentioned in the content.

A

Stable angina, also known as angina pectoris, refers to myocardial ischemia without myocardial necrosis, presenting as chest pain that can be managed with detailed history-taking and appropriate treatment.

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10
Q

What is the significance of taking a full detailed history for patients presenting with chest pain, according to the content?

A

Taking a detailed history is essential to rule in or rule out symptoms associated with angina, aiding in the diagnosis and management of patients with chest pain.

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11
Q

Describe the symptoms associated with stable angina.

A

Exertional symptoms like heaviness and tightness that improve with rest and GTN, more common in patients with high atherosclerotic cardiovascular risk.

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12
Q

What is the recommended approach for patients with ongoing symptoms of stable angina after medical therapy?

A

Revascularization to improve coronary blood flow, with options like coronary artery bypass grafting over balloon and stents for some individuals.

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13
Q

Define the diagnostic evaluation process for stable angina.

A

Includes non-invasive tests to look for symptoms reproduction or myocardial ischemia, and invasive angiography if ongoing symptoms or concerns persist.

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14
Q

How does medical therapy help in managing stable angina symptoms?

A

It helps alleviate symptoms, but for patients with persistent symptoms, revascularization may be offered to improve coronary blood flow.

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15
Q

Describe the potential benefits of coronary artery bypass grafting over balloon and stents for some patients with stable angina.

A

A small group may benefit prognostically from a lifespan perspective, although there are small risks and no lifetime guarantee.

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16
Q

Describe the cornerstone features of stable angina symptoms.

A

Symptoms occur on exertion, are relieved by rest reproducibly, and respond rapidly within seconds to minutes to GTA.

17
Q

What is an essential part of evaluating someone for stable angina?

A

A 12 Lead ECG, which needs to be studied and reported.

18
Q

How can investigations for stable angina be categorized?

A

Into those that reproduce symptoms (like an exercise test), show myocardial ischemia, or show consequences of ischemia.

19
Q

Define disease modifying therapy for atheromatous coronary artery disease.

A

It involves treatments like statins and antiplatelet agents to modify the progression of the disease.

20
Q

Do patients with high cardiovascular risk factors have a higher likelihood of stable angina?

A

Yes, patients with excess cardiovascular risk or high cardiovascular risk are more likely to have stable angina.

21
Q

Describe the treatment approach for patients with symptoms requiring antiantinals.

A

Patients may need more than one antianginal medication to control their symptoms, typically focusing on those that reduce arterial blood pressure.

22
Q

What are the two main methods for coronary revascularization mentioned in the content?

A

Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG).

23
Q

Define the purpose of coronary revascularization in patients with ongoing symptoms.

A

It aims to alter coronary blood flow to restore it to normal, improving symptoms and potentially prognosis.

24
Q

How is coronary artery bypass grafting (CABG) typically reserved in clinical practice?

A

It is often reserved for patients with multivessel or severe coronary disease.

25
Q

Describe the potential outcomes and considerations associated with coronary artery bypass grafting (CABG) mentioned in the content.

A

CABG can improve symptoms and has a small evidence base for improving prognosis, but may require additional medications and pose risks like increased bleeding.