Signaling Pathway for Hormones Flashcards

1
Q

GH

A

Non-Receptor TK

JAK/STAT

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2
Q

GHRH

A

Gs cAMP

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3
Q

What other hormones use cAMP?

A

Calcitonin, GHRH, Glucagon

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4
Q

ACTH

A

Gs cAMP

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5
Q

PTH

A

Gs cAMP

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6
Q

Gastrin

A

Gq IP3

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7
Q

hCG

A

Gs cAMP

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8
Q

Glucagon

A

Gs cAMP

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9
Q

cGMP hormones

A

BNP, ANP, EDRF (NO)

think vasodilators

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10
Q

ADH (V2)

A

Gs cAMP

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11
Q

Non-receptor Tyrosine Kinases PIGGLET

A

Prolactin, immunomodulators (IL-2, IL-6, IFN), GH, G-CSF, EPO, Thrombopoeitin
JAK/STAT Pathway
Think Acidophils and cytokines

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12
Q

Prolactin

A

Non-Receptor TK

JAK/STAT

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13
Q

FSH

A

Gs cAMP

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14
Q

LH

A

Gs cAMP

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15
Q

Receptor Tyrosine Kinase

A

Insulin, IGF-1, FGF, PDGF, EGF

MAP Kinase pathway, think growth factors

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16
Q

IL-2, IL-6, IFN

A

Non-Receptor TK

JAK/STAT

17
Q

What are the acidophils of Anterior Pituitary?

A

GH, PRL

18
Q

Histamine (H1)

A

Gq IP3

19
Q

Calcitonin

A

Gs cAMP

20
Q

ADH (V1)

A

Gq IP3

21
Q

GOAT HAG mnemonic

A

IP3

GnRH, Oxytocin, ADH (V1), TRH, Histamine (H1), Ang II, Gastrin

22
Q

TRH

A

Gq IP3

23
Q

GnRH

A

Gq IP3

24
Q

Oxytocin

A

Gq IP3

25
Q

Ang II

A

Gq IP3

26
Q

Intracellular Receptors PET CAT on TV

A

Progesterone, Estrogen, Testosterone, Cortisol, Aldosterone, T3/T4, Vit D

27
Q

Insulin

A

Receptor TK

MAP Kinase

28
Q

MSH

A

Gs cAMP

29
Q

G-CSF, EPO, Thrombopoietin

A

Non-Receptor TK

JAK/STAT

30
Q

What are the basophils of Anterior Pituitary?

A

FSH, LH, ACTH, TSH

31
Q

FLAT ChAMP mnemonic

A

cAMP
FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2), MSH, PTH
Think of basophils

32
Q

IGF-1

A

Receptor TK

MAP Kinase

33
Q

CRH

A

Gs cAMP

34
Q

TSH

A

Gs cAMP