Signaling Pathway for Hormones Flashcards
GH
Non-Receptor TK
JAK/STAT
GHRH
Gs cAMP
What other hormones use cAMP?
Calcitonin, GHRH, Glucagon
ACTH
Gs cAMP
PTH
Gs cAMP
Gastrin
Gq IP3
hCG
Gs cAMP
Glucagon
Gs cAMP
cGMP hormones
BNP, ANP, EDRF (NO)
think vasodilators
ADH (V2)
Gs cAMP
Non-receptor Tyrosine Kinases PIGGLET
Prolactin, immunomodulators (IL-2, IL-6, IFN), GH, G-CSF, EPO, Thrombopoeitin
JAK/STAT Pathway
Think Acidophils and cytokines
Prolactin
Non-Receptor TK
JAK/STAT
FSH
Gs cAMP
LH
Gs cAMP
Receptor Tyrosine Kinase
Insulin, IGF-1, FGF, PDGF, EGF
MAP Kinase pathway, think growth factors
IL-2, IL-6, IFN
Non-Receptor TK
JAK/STAT
What are the acidophils of Anterior Pituitary?
GH, PRL
Histamine (H1)
Gq IP3
Calcitonin
Gs cAMP
ADH (V1)
Gq IP3
GOAT HAG mnemonic
IP3
GnRH, Oxytocin, ADH (V1), TRH, Histamine (H1), Ang II, Gastrin
TRH
Gq IP3
GnRH
Gq IP3
Oxytocin
Gq IP3
Ang II
Gq IP3
Intracellular Receptors PET CAT on TV
Progesterone, Estrogen, Testosterone, Cortisol, Aldosterone, T3/T4, Vit D
Insulin
Receptor TK
MAP Kinase
MSH
Gs cAMP
G-CSF, EPO, Thrombopoietin
Non-Receptor TK
JAK/STAT
What are the basophils of Anterior Pituitary?
FSH, LH, ACTH, TSH
FLAT ChAMP mnemonic
cAMP
FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2), MSH, PTH
Think of basophils
IGF-1
Receptor TK
MAP Kinase
CRH
Gs cAMP
TSH
Gs cAMP
