Signaling molecules. (Interleukins) Flashcards

1
Q

IL-1

A

inflammation

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2
Q

IL-6

A

neutrophil differentiation. Fever inducer

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3
Q

IL-23

A

stimulate IL-1, IL-6, TNF release. Pro-inflammatory

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4
Q

IL-27

A

improve Ag recognition among B/T cell

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5
Q

IFN-alpha, beta

A

anti-viral. pro-inflamatory

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6
Q

TNF- alpha

A

Pro-inflammatory, fever producing. Increase acute phase proteins

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7
Q

IL-2

A

Increase Ab secretion. Improve T and NK cell growth

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8
Q

IL-4

A

Reduce amount of IL-12. Differentiates T cell. Improve Ab secretion

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9
Q

IL-5

A

Raise B cell growth. Activate eosinophils.

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10
Q

IL-12

A

Activate NK and Tc cells

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11
Q

IL-17

A

Form TNF, IL-1, IL-6. all pro-inflammatory

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12
Q

IFN-gamma

A

Increase Tc cells. Antiviral response. Increase macrophage phagocytosis.

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13
Q

TNF- beta

A

imrpove B/T cell differentiation. increase CSF-2, -3

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14
Q

IL-3

A

forms myeloid progenitor cells

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15
Q

IL-7

A

forms lymphoid progenitor cells

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16
Q

CSF-1

A

hematopoietic stem cell inducer to monocyte/macrophages

17
Q

CSF-2

A

turn hematopoietic stem cells into granulocytes

18
Q

CSF-3

A

turn hematopoietic stem cells into neutrophils