Signaling molecules. (Interleukins) Flashcards
IL-1
inflammation
IL-6
neutrophil differentiation. Fever inducer
IL-23
stimulate IL-1, IL-6, TNF release. Pro-inflammatory
IL-27
improve Ag recognition among B/T cell
IFN-alpha, beta
anti-viral. pro-inflamatory
TNF- alpha
Pro-inflammatory, fever producing. Increase acute phase proteins
IL-2
Increase Ab secretion. Improve T and NK cell growth
IL-4
Reduce amount of IL-12. Differentiates T cell. Improve Ab secretion
IL-5
Raise B cell growth. Activate eosinophils.
IL-12
Activate NK and Tc cells
IL-17
Form TNF, IL-1, IL-6. all pro-inflammatory
IFN-gamma
Increase Tc cells. Antiviral response. Increase macrophage phagocytosis.
TNF- beta
imrpove B/T cell differentiation. increase CSF-2, -3
IL-3
forms myeloid progenitor cells
IL-7
forms lymphoid progenitor cells