Signaling disease Flashcards

0
Q

Pancreatic cancer

A

Mutation in SMAD

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1
Q

Kennedy’s disease

A

Mutation in androgen receptor

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2
Q

Noonan and Costello syndromes

A

Mutation in Ras

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3
Q

Familial adenomatous polyposis

A

Mutation in WNT

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4
Q

Acute promyelocytic leukemia

A

Mutation in retinoic acid receptor

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5
Q

Whooping cough

A

Mutation in Gi

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6
Q

Familial hypertrophic cardiomyopathy

A

Mutation in Ca+2 function

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7
Q

Cushing syndrome

A

Mutation in glucocorticoid receptor

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