Sievert Embryo / Hulka Anatomy Week 1 Flashcards
An abdominal resection is a _______ surgery
a) biliary
b) intestinal
c) gynecologic
d) gastric
D gastric
A midline incision goes through the ______ and is the strongest area to close. Nerve injury is minimal.
linea alba
A transverse incision goes through the __________. Nerve injury is minimal but may be weaker incision.
external and internal obliques, transversus and possible rectus muscles
True/False: Laparoscopic surgery uses small incisions so there are less chances of hernias and quicker recovery
True
What are three contraindications to laparascopic surgery?
prior abdominal surgeries, emergency, advanced pregnancy
During laparascopic surgery, the abdomen is filled with CO2. Why is CO2 used rather than O2 and helium?
CO2 is not flammable, easily absorbed in body and gotten rid of through exhalation
How is advanced pregnancy a contraindication for laparascopic surgery?
Can’t give too much CO2 or will cause preterm labor
What is a hernia? (basic definition)
weakness in the muscle allows a organ to bulge through it. can be either developmental or acquired.
____ of men and ___ of women will have an inguinal hernia in their lifetime
25, 2
List hernias in order of most to least common: epigastric femoral inguinal umbilical ventral/incisional
inguinal - 75% ventral/incisional - 10% umbilical - 6% femoral - 3% epigastric - unk
True/False: In children, inguinal hernias should not be fixed because they will normally go away
FALSE
Won’t go away, will get larger, possibility in incarceration/strangulation
True/False: In adults, all hernias should be fixed
FALSE
watching waiting for small, asymp hernias is OK but likely will need surgery at some point
What is the difference between an incarcerated and strangulated hernia?
Incarcerated - cannot be reduced because too occluded
Strangulated - blood supply cut off, risk of infarct
Do umbilical hernias normally have to be fixed in children? adults?
In children, they will often close by age of 2 years. if they don’t close by then or they are symptomatic, then repair.
In adults, repair.
True/False: All muscles of anterior abdominal wall contribute to inguinal canal
True
The inguinal canal is the _______ aspect of the abdominal wall, located above the fold of the leg and is divided into right and left by the ________
inferior, linea alba
True/False: Indirect hernias go through Hesselbach’s triangle
FALSE - direct do
True/False: Indirect hernias go through patent processus vaginalis usually
TRUE
Body folding incorporates both the gut tube and the coelom in the embryo. How many coelomic cavities are incorporated in the body cavity during folding?
2
The primitive gut tube is supported btwn the linings of the 2 coelomic sacs called _____. Initially, there is a dorsal and ventral layers the entire length of the gut tube, but the ______ later deteriorates through most of the tube
mesenteries; ventral layer
As folding progresses, the yolk sac gets pinched down to form a gut tube with a stalk called the ______ connecting to the remaining yolk sac.
vitelline duct
From which primitive germ layer does the:
a) mucosa and glands of GI
b) surrounding connective tissue and smooth muscle
c) dorsal mesentery
develop?
a) mucosa and glands of GI are from endoderm
b) surrounding CT and smooth muscle comes from splanchnic mesoderm of lateral plate
c) splanchnic mesoderm of lateral plate
What are the mesenteries? (3 features)
- lining of coelomic sacs from each side of the gut tube
- pathways for vessels and nerves to reach abd organs
- persist only when necessary
True/False: Retroperitoneal structures include the aorta, vena cava, and kidneys
True
The dorsal mesentery is found throughout most of the entire length of the abd gut tube. The ventral mesentery, however, is only found in which regions?
The region of the foregut which supports the liver and gall bladder
What are the two component of the ventral mesentery that remain in an adult?
lesser omentum, falciform ligament
How does the mesentery become 4 layers when it starts out as two?
It is a two layer sac that lays on itself.
As it pooches out, comes down on stomach and goes back to wall.
In what area do the two separate coelomic sacs become one after the ventral mesentery disappears?
below the foregut
[mid-gut and hindgut in lower cross section]
Describe how peritonealization relates to the mesentery.
most of the gut tube has a mesentery initially, but some structures lose their mesentery duringfuture development.
structures that never have a mesentery are primarily retroperitoneal
structures that lose their mesentery are secondarily retroperitoneal
Name 4 organs that are secondarily retroperitoneal
- pancreas
- descending colon
- ascending colon
- duodenum
Describe the defining boundaries of the
a) foregut
b) midgut
c) hindgut
a) foregut begins just past the opening of the bile duct and pancreatic duct in the duodenum
b) midgut includes the rest of the duodenum to the distal 1/3 of transverse colon
c) hindgut includes the distal 1/3 of the transverse colon to the proximal anal canal
Describe the artery to the
a) foregut
b) midgut
c) hindgut
a) foregut - celiac trunk
b) midgut - superior mesenteric artery
c) hindgut - inferior mesenteric artery
Describe the rotation of the foregut and how this creates the greater omentum.
The stomach undergoes a 90 degree rotation with the anterior surface turning to the right.
The greater curvature of the stomach expands.
The dorsal mesentery also needs to expand to accomomdate both growth and rotation which creates the greater omentum.
Describe the difference between the great omentum and the lesser omentum.
The greater omentum is a large apron-like fold of visceral peritoneum that hangs down from the stomach.
The lesser omentum hangs down from the liver to the lesser curvature of the stomach and first part of duodenum.
True/False: The liver, gallbladder and two pancreatic buds are all attached to the duodenum at the same place.
False - only the ventral pancreatic bud is attached to duodenum at same place as liver and gallbladder.
The dorsal pancreatic bud is separate.
Differential growth and rotation in the wall of the duodenum moves the opening of the bile duct around to the ______ surface
dorsal surface
What happens to the dorsal and ventral pancreatic buds during development?
The dorsal bud eventually merges with the duct from the ventral bud
The ventral bud therefore becomes the main one
Only a short accessory duct remains
Describe midgut rotation.
Prior to rotation, the midgut loop is centered on the superior mesenteric artery with the cecum, ascending, transverse, and descending colons in the caudal half of the loop.
Rotation occurs CCW from anterior surface.
Rotation is about 270 degrees around the SMA.
Results of rotation - The 4th part of the duodenum is trapped under the SMA. The colon frames the small bowel around the periphery. The cecum is put in the lower right quadrant. Descending colon on the left side.
When does midgut rotation begin and where does it occur?
Midgut rotation starts at about the 10th week when the midgut loops begins to enter the abdomen. The first stages occur outside of the fetus due to rapid growth of the tube relative to the fetus, but the final stages take place in the abd cavity.
What is volvulus and why can it be dangerous?
Any form of abnormal rotation of parts of the gut tube.
This can be dangerous because of potential for disrupting blood supply and causing gangrene.
What is gatroschisis?
How common is the occurrence and in which populations is it even more common?
What is the survival rate?
Gastroschisis occurs when the lateral walls of the abdomen do not close completely and the expanding GI tract protrudes through the opening.
1:2K occurrence. More common in young mothers who used alcohol, tobacco, or NSAIDs.
It is not usually assoc with chromosomal abnormalities or other defects, so survival rate after GW35 is excellent
How does intestinal damage occur from gastroschisis?
the herniation is lateral to the connecting stalk
not covered by amnion
amniotic fluids damages intestines
causes malabsorption due to intestinal damage
What is omphalocele?
How common is this defect?
What is the survival rate?
Omphalocele - herniation of abd viscera through an enlarged umbilical ring; due to a failure of intestinal loops to return to body cavity from umbilical cord after normal herniation during W6-W10.
1/4000 births so common defect
High rate of infant mortality and numerous other severe congenital defects
True/False: An omphalocele hernial sac is always covered with the epithelium of the umbilical cord, a derivative of the amnion
TRUE
Describe Meckel’s or ileal diverticulum.
Most common GI developmental abnormality
Small portion of vitelline duct persists
Therefore, diverticulum is a remnant of the yolk sac.
Affects 2-4% of all people
Asymptomatic
There may be ulceration, bleeding or perforation in the adult however.
Describe the rule of 2 in Meckel’s diverticulum
2% of popn
2 feet from ileocecal valve
2 inches in length
2% symptomatic
2 types of common ectopic tissue [gastric and pancreatic]
2 years is most common age of presentation
2X more common in males
Describe the pectinate line in hindgut development and its significance in terms of sensory innervation.
The portion of the anal canal from the rectum to the pectinate line is derived from endoderm - no sensory innervation - why you can’t feel internal hemorrhoids.
The portion of the anal canal from the pectinate line to the anus is derived from the ectoderm - sensory innervation - why you can feel external hemorrhoids.
An example of a hindgut abnormality is Hirschsprung disease or aganglionic megacolon. Describe.
Failure of migration of neural crest cells into the developing gut tube.
Affects rectum and sigmoid colon
Results in a section of the gut tube which is lacking ganglia and unable to contract
What is an imperforate anus?
There is a persistent anal membrane [no anal opening]
What is a rectovaginal fistula or in male rectovesicle?
Rectovaginal fistula - The rectum connects to the vagina
Rectovesicle - rectum connects to urinary bladder in males
Describe the descent of the testes.
The testes develop intraabdominally while the fetus is in utero [retroperitoneal]
The testes descend through the deep ring, down inguinal canal to the scrotum.
- This brings peritoneum with the testicle forming tunica vaginalis
- Communication between the abdomen and the scrotum is called the processus vaginalis. This structure obliterates after birth to become the tunica vaginalis.
The deep ring includes what two abdominal muscles
internal oblique
transversus abdominis
The top of the inguinal canal is made up of the ______ and the bottom is the ________
external oblique, inguinal ligament
True/False: Indirect hernias tend to be acquired whereas direct tend to be congenital or development
FALSE - the opposite is true.
direct tend to be acquired
indirect tend to be congenital or development [due to patent process vaginalis]
What two inner abdominal muscles make up the arching fibers associated with the weak area of the triangle? [their tendons create the conjoint tendon]
transversus abdominis
internal oblique
Where is the weak area of the triangle located?
medial to the deep ring
in the inguinal triangle
Where do femoral hernias tend to protrude? In which sex are they more common?
Through femoral ring below inguinal ligament
more common in women
How do you check for inguinal hernias in men? Women?
Men - invaginate skin between scrotum and penis into the inguinal canal, go through superficial inguinal ring
women - place hand over inguinal canal and have them inc abd pressure
The inguinal canal extends from the ______ to the _______
anterior iliac crest, inguinal tubercle
How are indirect hernias fixed?
via high ligation of sac
How were direct hernias originally fixed? What is the current standard?
Direct hernias were historically treated by bringing the muscles together with sutures but this lead to complications incl inc pain and high recurrence.
Mesh repairs were used from the 1960s to 80s
Led to inflammatory/scar rxns [now put mesh over peritoneum to protect the bowel]
Started to do laparascopic surgeries in 1990s
How are inguinal hernias fixed?
Open surgery is used for unilateral, first time hernia repairs, pts with prior lower abd surgery
Laparascopic for bilat or recurrent hernias
Fermoral hernias occur inferior to the inguinal ligament. Describe the inferior, medial, and superior borders of femoral hernias
Inferior border - pectineal ligament
Superior border - inguinal ligament
Medial border - lacunar ligament
How are femoral hernias usually repaired?
via mesh repair either below the inguinal ligament or above
Gastroschisis or omphaloceles develop when muscles do not fuse after bowel extrudes from the abdomen during gestational weeks ______
6-8
There are many theories as to the cause of abdominal wall defects. What is one that involves an umbilical artery?
Most likely due to obliteration of right umbilical artery which causes a wall defect
How was gastroschisis treated in the past versus now?
Before, would just shove organs into abdomen. However, since lungs are huge and bad cavity is very small in this infant it is better to silo the organs in a dependent position and over the course of a few days, move them in to stretch out the abdominal cavity.
The internal oblique muscle gives rise to the ______
cremaster muscle
Describe the cremasteric reflex and its afferent/efferent paths.
Stroking of the inner thigh –> elevation of ipsilateral testicle
Afferent path - spinal cord at L1,L2
Efferent path - genitofemoral nerve to cremaster muscle
An absent cremasteric reflex is highly (96%) specific for what condition?
testicular torsion
surgical emergency
[within 6 hours - still 90% effective in salvaging testicle]
What is a hydrocele?
liquid in the area of the tunica vaginalis
water next to the testicle basically
The ______ connects the liver to the peritoneum
falsiform
Name the three folds and their components
1) Median umbilical fold=obliterated urachus
2) Medial umbilical fold=obliterated umbilical artery
3) Lateral umbilical fold=inferior epigastric vessels
Describe the types of cells that are part of the
a) neurogenic
b) myogenic
components of GI neurophysiology
a) neurogenic - CNS, ENS
b) myogenic - interstitial cells of cajal, smooth? muscle
The abdominal aorta is a continuation of the _______ and begins at the ______ as it enters the abdomen through the diaphragm at the _____ vertebral level
thoracic aorta, aortic hiatus, T12-L1
How and where does the abdominal aorta end?
It ends by dividing into 2 common iliac arteries above the pelvis at the L4-L5 vertebral level.
True/False: Almost every organ in the abdominal cavity gets its blood supply from more than one place.
True - DUE TO COLLATERAL CIRCULATION
What are the seven major branches off the abdominal aorta? Which are mesenteric?
phrenic branch celiac trunk - mesenteric superior mesenteric artery - mesenteric inferior mesenteric artery - mesenteric renal arteries gonadal arteries lumbar arteries
The phrenic branch is the first branch off the aorta and runs inferior to the _______. it gives rise to one of the _____ arteries and blood supply to the inferior surface of the ______
diaphragm, adrenal, diaphragm
Basically, the phrenic branch gives branches to the ______ and ______
adrenal gland, diaphragm
The celiac branch is the first ____ branch of aorta and arises at approximately the ____ vertebral level.
mesenteric, T12
What are the three branches off the celiac trunk?
left gastric, common hepatic, splenic
The left gastric artery exits the celiac trunk to the ___ and courses towards the ______ of the stomach. It provides blood supply to the ______ and _____
left, right side, lower esophagus, lesser curvature of the stomach