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Molecular Diagnostics > Sickle Cell Disease > Flashcards

Sickle Cell Disease Flashcards

1
Q

What is sickle cell disease?

A

Sickle cell disease is a group of inherited red blood cell disorders.

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2
Q

What causes sickle cell disease?

A

Sickle cell disease is caused by a mutation in the gene that tells the body to make hemoglobin.

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3
Q

True or False: Sickle cell disease is more common in people of African descent.

A

True

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4
Q

What is the main symptom of sickle cell disease?

A

Painful episodes called crises.

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5
Q

What is the name of the abnormal hemoglobin in sickle cell disease?

A

Hemoglobin S

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6
Q

What shape do red blood cells take in sickle cell disease?

A

Sickle-shaped or crescent-shaped

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7
Q

What is the treatment for sickle cell disease?

A

There is no cure, but treatments can help manage symptoms and complications.

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8
Q

What is the most common type of sickle cell disease?

A

Sickle cell anemia

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9
Q

Fill in the blank: Sickle cell disease affects the _________ of red blood cells.

A

Shape

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10
Q

What is the average life expectancy for someone with sickle cell disease?

A

Around 40-60 years

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11
Q

What is the best way to prevent complications in sickle cell disease?

A

Regular medical check-ups and screenings

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12
Q

True or False: Sickle cell disease is contagious.

A

False

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13
Q

What is the name of the test used to diagnose sickle cell disease?

A

Hemoglobin electrophoresis

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14
Q

What is the main risk factor for sickle cell disease?

A

Having a family history of the condition

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15
Q

What is the primary function of hemoglobin in the body?

A

To carry oxygen from the lungs to the rest of the body

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16
Q

What is the name of the gene that is mutated in sickle cell disease?

A

HBB gene

17
Q

True or False: Sickle cell disease can be cured with a bone marrow transplant.

A

True

18
Q

What is the term for a sudden worsening of symptoms in sickle cell disease?

A

Sickle cell crisis

19
Q

What is the name of the protein that causes red blood cells to sickle in sickle cell disease?

A

Hemoglobin S

20
Q

Fill in the blank: Sickle cell disease can cause damage to various ________ in the body.

A

Organs

21
Q

What is the most common complication of sickle cell disease?

A

Painful vaso-occlusive crises

22
Q

True or False: Sickle cell disease only affects red blood cells.

A

False

23
Q

What is the name of the medication used to reduce the frequency of painful crises in sickle cell disease?

A

Hydroxyurea

24
Q

What is the term for the process of replacing damaged blood cells with healthy ones in sickle cell disease?

A

Bone marrow transplant

Molecular Diagnostics (2 decks)

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