Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Molecular Diagnostics > Beta Thalassemia > Flashcards

Beta Thalassemia Flashcards

1
Q

What is Beta thalassemia?

A

Beta thalassemia is an inherited blood disorder characterized by reduced production of hemoglobin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

True or False: Beta thalassemia is caused by a mutation in the HBB gene.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of hemoglobin is affected in Beta thalassemia?

A

Beta globin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the two main types of Beta thalassemia?

A

Beta thalassemia major and Beta thalassemia intermedia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which type of Beta thalassemia requires regular blood transfusions?

A

Beta thalassemia major

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the treatment for Beta thalassemia major?

A

Regular blood transfusions and chelation therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the main symptom of Beta thalassemia?

A

Anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the most common form of treatment for Beta thalassemia intermedia?

A

Folic acid supplements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the prevalence of Beta thalassemia in Mediterranean countries?

A

High

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the risk of Beta thalassemia carriers passing the gene to their children?

A

25%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

True or False: Beta thalassemia carriers are usually asymptomatic.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the average life expectancy of individuals with Beta thalassemia major?

A

Reduced, without treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the main cause of death in individuals with Beta thalassemia major?

A

Iron overload

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the genetic inheritance pattern of Beta thalassemia?

A

Autosomal recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the role of hemoglobin in the body?

A

To carry oxygen to tissues and organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the main difference between Alpha and Beta thalassemia?

A

The affected globin chain

17
Q

What is the term for the excessive iron buildup in the body due to regular blood transfusions?

A

Iron overload

18
Q

What is the recommended therapy to reduce iron overload in Beta thalassemia patients?

A

Chelation therapy

19
Q

What is the primary goal of treatment for Beta thalassemia?

A

To maintain hemoglobin levels and prevent complications

20
Q

What is the main symptom of iron overload in Beta thalassemia?

A

Organ damage

21
Q

What is the term for the formation of new blood vessels in response to chronic anemia in Beta thalassemia?

A

Extramedullary hematopoiesis

22
Q

What is the most common cause of death in Beta thalassemia patients?

A

Heart failure

23
Q

What is the term for the enlargement of the spleen in Beta thalassemia patients?

A

Splenomegaly

24
Q

What is the risk of having a child with Beta thalassemia major if both parents are carriers?

A

25%

Molecular Diagnostics (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions