Sickle Cell Anemia

Question 1

Sickle Cell Anemia is

Answer 1

Hemolytic anemia, Herdiatry disease caused by mutation in beta chain of hemoglobin

Question 2

Hb seen in sickle

Answer 2

In homozygous:
90% is Hbs , remain is HbA2 and Hbf

In heterozygous:
50% Hbs , remain is HbA ( this called sickle cell trait)