Shokry Material

Question 1

Drug of Choice for Emergency treatment of Life threatening Bronchoconstriction

Answer 1

Epinepherine

*Short acting- less than 1 hour. Administered as a Single Treatment

Question 2

Drug used for Long Term Treatment of Bronchio-asthma in Cats and Recurrent Airway Obstruction in Horses

Answer 2

Terbutaline

Question 3

Drug approved in Cats and Horses as a Bronchodilator that is Administered orally or by Inhalation. Aerosol is Approved in Horses

Answer 3

Albuterol

Question 4

Stimulation of ____ Receptors causes Bronchodilation, and stabilization of mast cells, and increases mucociliary clearance

Answer 4

B2

Question 5

Main use of _____ Selective Agonists is Bronchodilators to treat and prevent acute bronchoconstriction due to bronchial asthma in cats or Recurrent Airway Obstruction in Horses

Answer 5

B2

Question 6

Respiratory Effects of which drugs include Bronchodilation, Antiinflammatory, Prevention of Microvascular Leakage, Stimulating Mucociliary Clearance, and Improve Breathing

Answer 6

Methylxanthine Derivatives

*Activation on muscle because they stimulate the CNS = Improved Breathing

Question 7

Antiinflammatory Drug that Inhibits Mast cell release of Histamine that is occassionally used in animals to stabilize mast cells with Hypersensitive Airways and Is Administered to Horses Prophylactically in the treatment of Recurrent Airway Obstruction

Answer 7

Cromolyn Sodium

*Has no Bronchodilation effect. It is used to Prevent, not to treat Allergic Reactions

Question 8

Leukotrienes Inhibitors are used to Treat ______, but are not affecting in Managing Asthma or Bronchoconstriction

Answer 8

Congestion

*Decongestion to treat Nasal Congestion

Question 9

NSAID that is used in Horses and Dogs to Treat Pulmonary Effects of Endotoxin and are Certified as an Adjunct treatment of Bovine Respiratory Disease in Cattle

Answer 9

Flunixin

*Treatment of BRD

Question 10

Antiplatalet drug that can be used for the treatment of Pulmonary Thromboembolism in small animals

Answer 10

Aspirin

*Antiplatelet Drug

Question 11

Drugs that Decrease the Frequency and Severity of Nonproductive cough without impairing mucociliary Defenses

Answer 11

Antitussives

Question 12

Antitussive that is considered the First Drug of choice for symptomatic treament of cough in Dogs

Answer 12

Hydrocondone

Question 13

Drug that has a Potent Antitussive effect in dogs with a duration of action between 4-10 Hours

Answer 13

Butorphanol

Question 14

Inexpensive and Not Controlled Drug that is an effective antitussive in dogs

Answer 14

Tramadol

*Good- Inexpensive and Not Controlled

Question 15

Drugs that Facilitate the Removal of Secretions from the Respiratory Tract by stimulating Ciliary Activity

Answer 15

Mucokinetic Drugs

Question 16

Drugs that Increase the Volume and Fluidity of Respiratory Secretions

Answer 16

Expectorants

*Ex. Potassium Iodide and Ammonium Salts

Question 17

Expectorant that causes Direct Stimulation to increase the Volume and Fluidity of Respiratory Secretions

Answer 17

Guaifenesin

*Potassium Iodide and Ammonium salts are Expectorants that work Indirectly by Irritation of Gastric Mucosa

Question 18

Three commonly used Oral Decongestants that work via Vasoconstriction

Answer 18

Ephedrine

Pseudoephedrine

Phenylpropanolamine (PPA)

*Three are commonly used as Oral Decongestants

Question 19

Vasoconstrictors (Ex. Ephedrine), Cromolyn Sodium and Glucocortioids are all used as _____

Answer 19

Decongestants

Question 20

Three H1-antagonists that are used as Decongestants

Answer 20

Diphenhydramine (Benadryl)

Promethazine

Cyproheptadine

Question 21

Diuretic used to Tread Pulmonary Edema

Answer 21

Furosemide

Question 22

Two Drugs used as Antifoaming Agents

Answer 22

Nebulization of Ethyl Alcohol

Silicone Spray

Question 23

_____ is used to Treat Hypoxemia and Respiratory Acidosis due to Hypoventilation that is administered via Face mask, Intubation or Nasal Tubes

Answer 23

Oxygen

Question 24

Drug approved in Dogs, Cats and Horses as an Analeptic to stimulate the Breathing Muscles and Increase Respiration

Answer 24

Doxapram

*Used for reversal of respiratory depression due to anesthesia and to stimulate respiration in a neonate when it is depressed

Question 25

Drug used to Treat Malassezia Canis, a Yeast which causes ear infections

Answer 25

Tolnaftate

Question 26

Drug given Orally for treatment of Dermatophytes, local Fungal Infection

Answer 26

Griseofulvin \*Has to be given Systemically

Question 27

True/False: Most antifungal drugs act on the cell membrane

Answer 27

True \*Know this Picture!

Question 28

Antifungals that Attack the Fungal Cell Membrane, such as Imidazoles and Triazoles, inhibit the ______ enzyme, blocking the synthesis of Ergosterol that is necessary for Fungal Membrane Development and Maintenance

Answer 28

14a-demethylase

Question 29

Drugs that Produce Squalene Epoxidase which Inhibits the production of Squalene Epoxide, which is necessary for Ergosterol Synthesis

Answer 29

Allylamines \*Ex. Terbinafine

Question 30

Drugs that are Fungicidal due to Rapid Alteraltion of Fungal Cell membrane permeability by binding irreveribly to Ergosterol

Answer 30

Polyenes

Question 31

Drugs that are Fungistatic due to alteration of Fungal cell permeability by blocking conversion of Ianosterol to Ergosterol, which is catalyzed by 14-a demethylase

Answer 31

Azoles

Question 32

Drug that is Fungistatic that inhibits Fungal Nuclear Division due to interference with Microtubule function and inhibiting Mitosis

Answer 32

Griseofulvin

Question 33

Drug that is Fungicidal due to Inhibition of Nucleic Acid Synthesis by inhibiting thymidylate Synthase

Answer 33

Flucytosine

Question 34

Drug that Inhibits Fungal Cell wall synthesis

Answer 34

Lufenuron \*Only antifungal that acts on the cell wall

Question 35

Drug given IV that is Extremely Nephrotoxic that is the most effective drug for treatment of Systemic Mycoses in immuno-compromised Animals

Answer 35

Amphotericin B \*Nephrotoxic- never use in Renal Disease. Most Nephrotoxic Drug in Existance

Question 36

Drug Given orally for broad-spectrum antifungal activity against Dermatophytes, Candida and Malassezia Canis in Immuno-comptetant Patients that requires acidic pH for Absorption

Answer 36

Ketoconazole \*Given after meals when pH is more Acidic. Only effective in non-immuno-compromised animals.

Question 37

Drug that is the Preferred drug for systemic Blastomycosis and Histoplasmosis that is similar to Ketoconazole but does not depend on acidity. This drug is also effective agasint Aspergillosis and is the drug of choice for Sporotrichosis

Answer 37

Itraconazole \*One of the few effective against Aspergillosis

Question 38

Drug of choice to treat Crytococcal Meningitis in Cats that has good penetration to tissues and crosses the Blood Brain Barrier in the CNS

Answer 38

Fluconazole

Question 39

Drug used to Treat Apergillosis in Horses and Canine Nasal Aspergillosis

Answer 39

Clotrimazole