Shock Flashcards

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1
Q

Shock is a broad term that describes _____________________.

A

a physiologic state where oxygen delivery to the tissues is inadequate to meet metabolic requirements. It may also be thought of as an imbalance between tissue oxygen supply and demand.

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2
Q

Differentiate compensated and uncompensated shock.

A

Both compensated and uncompensated shock present with inadequate perfusion, but compensated shock is characterized by normal blood pressure. Uncompensated shock is characterized by low blood pressure.

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3
Q

Describe the four types of shock.

A
  • Hypovolemic (most common): decreased fluid volume –from hemorrhage or dehydration –leads to decreased perfusion
  • Cardiogenic: decreased cardiac output leads to decreased perfusion
  • Distributive: pathologic peripheral vasodilation leads to decreased perfusion; can be caused by infection, anaphylaxis, or neurogenic causes
  • Obstructive: non-cardiac obstruction to blood flow leads to decreased perfusion (such as pulmonary embolism, tension pneumothorax, tamponade, or constrictive cardiomyopathy
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4
Q

Paradoxically, early shock may present with elevated _________________.

A

blood pressure

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5
Q

What signs suggest shock?

A
  • Cool extremities
  • Dry mucous membranes
  • Pale extremities
  • Decreased capillary refill
  • Cyanosis
  • Thready pulses (rapid, scarcely palpable pulses)
  • Tachycardia
  • Hypotension

Other signs will be specific to the type of shock; for instance, tamponade will show JVD and sepsis will show fever.

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6
Q

What is the shock index?

A

HR/SBP

Normally it is 0.5 - 0.7. If it is greater than 1.0, this predicts worse outcome in shock.

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7
Q

Which types of shock present with increased HR?

A

All four types

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8
Q

Which types of shock present with increased CVP?

A

Cardiogenic and obstructive, because in both cases blood is not being moved by the heart

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9
Q

Which type of shock classically has decreased SVR?

A

Septic shock

Note: obstructive shock due to tension pneumothorax can have decreased SVR.

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10
Q

Describe what labs can show end-organ damage.

A

Lactate is an indicator of anaerobic metabolism in all tissues.

  • Brain: ischemic changes on CT; AMS
  • Heart: troponin; CK-MB; arrhythmia
  • Lungs: ARDS or edema on x-ray
  • Liver: elevated AST/ALT
  • Kidneys: elevated creatinine and BUN
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11
Q

Intubation is desirable in those with shock because it can reduce the metabolic load of breathing, but there are some disadvantages to it: ____________________.

A

(1) drugs used in intubation can cause negative hemodynamic effects; (2) PPV can further reduce SVR

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12
Q

Patients with shock are given fluids. Which conditions should you be cautious of in administering fluids?

A

Pulmonary edema

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13
Q

Shock is considered to be normalized when what things occur?

A
  • Normalization of hemodynamic parameters (BP, HR, urine output)
  • Lactate decreases
  • Resolution of acidosis
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14
Q

Vasopressors that also cause _____________ can be used to treat hypovolemic shock.

A

reuptake of fluid in the kidneys

Example: ddAVP

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15
Q

Distributive shock is kind of like hypovolemic shock. How?

A

In distributive shock, the vessels dilate too much. As such, the fluid is relatively low (it can’t fill the additional volume).

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16
Q

Sepsis is the most common cause of distributive shock, but ______________ can also cause it.

A

spinal cord injuries

17
Q

Why is epinephrine used to treat anaphylaxis?

A

A couple reasons: (1) it is a potent vasoconstrictor, (2) it leads to smooth muscle relaxation in the airway, and (3) it stabilizes mast cells

18
Q

Other than epinephrine, what treatments are given to those with anaphylaxis?

A
  • Antihistamines, both H1 and H2 antagonists

* Steroids

19
Q

List some of the causes of cardiogenic shock.

A
  • MI
  • Arrhythmia
  • Valvular stenosis
  • Ventricular rupture
  • Congestive heart failure
  • Myocarditis (common in children)
20
Q

List some of the causes of obstructive shock.

A
  • Pulmonary embolism
  • Tension pneumothorax
  • Tamponade
21
Q

What dose epinephrine is given in codes?

A

1 mg

22
Q

What is renal dosing of dopamine?

A

Lower doses of dopamine only affect the afferent arteriole, while higher doses target the alpha and beta adrenergic receptors too.

23
Q

Norepinephrine is first-line for ____________ shock.

A

distributive

24
Q

What does dopamine target at low and high doses?

A

Low: beta-1 and beta-2
High: alpha-1, beta-1, and beta-2

25
Q

What are some indications for central lines?

A
  • Vasopressors for longer than an hour; vasopressors can only be given peripherally for about an hour before becoming too constricted
  • Dialysis
  • Multiple medications that cannot be mixed
26
Q

Central lines are inserted into the __________ jugular.

A

internal

External jugular lines are not considered central lines.

27
Q

Mean arterial pressure (MAP) is equal to ____________.

A

CO x SVR

28
Q

Neurogenic shock specifically results from _________________.

A

injury to the sympathetic chain ganglion that disrupts sympathetic tone to the vasculature

29
Q

In addition to being found in the arteries, alpha-1 receptors are also found in the heart. What do the cardiac alpha-1 receptors do?

A

They increase conduction and excitation.

30
Q

Beta-1 stimulation causes increased _________________.

A

cardiac conduction and contractility