Shock Flashcards

1
Q

What is shock?

A

Shock is a syndrome characterized by decreased tissue perfusion and impaired cellular metabolism.

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2
Q

Cardiogenic shock

A

systolic or diastolic dysfunction of the heart’s pumping action results in reduced CO, Stroke Volume, and BP.

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3
Q

What side of the heart does systolic dysfunction occurs?

A

It mainly occurs in the L. ventricle b/c pressure is greater on L. side of the heart.

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4
Q

What is the most common cause of systolic dysfunction?

A

ACUTE MI

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5
Q

What are the causes of Cardiogenic shock?

A

Dysrythmias, (Bradydysrthmias, Tachydystryhtmia) strucutral factors(Valvular stenosis), Systolic Dysfunction (MI), Diastolic Dysfunction( Cardiac tamponade)

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6
Q

What is the patho of Systolic Dysfunction?

A

1) Ineffective forward movement of blood
2) Decreased Stroke Volume
3) Decreased CO
4) Decreased Cellular Supply
5) Decreased tissue !!perfusion
6) Impaired cellular metabolism!!

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7
Q

What are EARLY presentations of Cardiogenic shock?

A

similar to Acute Demcompensated HF.

Tachycardia with hypotension, pulse pressure is narrowed.
Upon assessment: -Tachypneic
-crackles on auscultation , increased
-Pulmonary artery wedge pressure.

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8
Q

What are signs of peripheral hypo-perfusion?

A

-cyanosis
-pallor
-diaphoresis
-weak peripheral pulses
-cool and clammy skin
-Delayed cap refill
-

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9
Q

What is hypovolemic shock?

A

occurs from inadequate fluid in the intravascular space to support adequate perfusion.

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10
Q

What is the differences between hypovolemic shock and cardiogenic shock?

A

Cardiogenic shock has to do with filling and pumping dysfunction of the heart that decreases perfusion and hypovolemic shock is inadequate fluid in the intravascular space.

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11
Q

What are the two types of hypovolemic shock?

A

-Absolute: Loss of fluid from (hemorrhage, GI(vomiting and diarrhea, diabetes insipidus, and urination.

  • Relative: Movement of fluid from intravascular space to the extravascular space (third spacing)
  • Burns
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12
Q

What are the consequences of absolute and relative fluid loss?

A

1) Decreased venous return
2) Decreased SV
4) Decreased CO
5) Impaired cellular metabolism.

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13
Q

What are the compensatory mechanism for fluid loss?

A

1) Patient can compensate for (15%) of total blood volume (750mL)
2) 15-30% blood loss results in SNS response(Increased HR, CO, RR. )
- Crystalloid can be given
3) Greater than 30% loss is immediate replacement of blood products
4) Greater than 40% irreversible tissue destruction.

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14
Q

What is neurogenic shock?

A

happens within 30 minutes of a spinal cord injury. Loss of SNS vasoconstrictor tone that leads to massive vasodilation causing pooling of blood in blood vessels, hypo-perfusion, and impaired cellular metabolism.

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15
Q

What are the classical manifestations of neurogenic shock?

A

-Bradycardia(classical)
-Hypotension(classical)
Other Manifestations:
-Not regulate temperature
-1st skin: warm –> then cold
(poikilothermia)

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16
Q

What is spinal shock?

A

Absence of voluntary and reflex below the level of injury.

17
Q

What is septic shock?

A

characterized by persistent hypotension, despite fluid resuscitation and inadequate tissue perfusion that results in tissue hypoxia.

18
Q

What are the main organisms that causes sepsis?

A

Gram -negative and gram positive bacteria

19
Q

What are the 3 pathophysiologic effects?

A

1) vasodilation
2) Maldistribution of of BF
3) myocardial depression

20
Q

What clinical presentation is common in shock?

A

Respiratory failure is common.

-Hyperventilation: leads to respiratory alkalosis then respiratory acidosis

21
Q

What is obstructive shock?

A

physical obstruction to blood flow with a decreased CO

22
Q

What causes obstructive shock?

A

1) restricted diastolic filling of the right ventricle from compression.
2) abdominal compartment syndrome
3) pulmonary embolism

23
Q

What is the initial stage of shock?

A
  • occurs at cellular level.
  • S/S usually not apparent
  • Metabolism: aerobic to anaerobic –> LACTIC BUILDUP
  • Liver metabolizes it, but not enough 02 because of decrease in tissue perfusion
24
Q

What is the compensatory Stage?

A
  • Classic sign is DROP in B/P
  • SNS is activated due to drop and maintains BF
  • BF to nonvital organs is diverted
25
Q

What happens when blood is shunted from the lungs?

A
  • V/Q mismatch as not enough air is being perfused to lungs

- Rate and depth of RR is increased

26
Q

What occurs to nonvital organs when blood flow is decreased?

A

1) GI: impaired motility and slowing of peristalsis (risk for paralytic ileus)
2) Skin: cool and clammy
3) Kidneys: RAAS is activited to increase BF and aldosterone is released to absorb water and sodium

27
Q

What are the important findings in Progressive Stage? (irreversible)

A

Patient’s MENTAL STATUS

28
Q

What happens to Cardio, Respiratory, GI, and Renal system in progressive?

A

C: Decrease in BP, edema, weak peripheral pulses, myocardial dysfunction
R: ARDS
G: erosive ulcers, GI bleeding, impaired absorption of nutrients
K: Renal tubular ischemia.. May lead to AKI, Decreased urine, increased BUN and creatine, Metabolic acidosis

29
Q

What is refractory stage?

A
  • Profound hypotension and hypoxemia
  • Cerebral ischemia
  • Recovery is unlikely
30
Q

What is given if patient does not respond to adequate fluid resuscitation?

A

-Vasopressor (NE, dopamine) and/or inotrope (dobutamine)

31
Q

What is the goal of vasopressor?

A

Achieve and maintain MAP greater than 65 mmHg

32
Q

What are drug therapies for Cardiogenic shock?

A

1) Decreased workload of heart (nitrates)
2) Reducing preload (Diurectics)
3) Reducing afterload (vasodilators)
4) HR and contractility (Beta adrenergic blockers)

33
Q

How to manage Septic shock?

A
  • Isotonic crystalloid solution
  • Passive leg raise
  • Vasopressors (NE)are given if no longer fluid responsive
  • antibiotics
  • Glucose
  • PPI and VTE prophylaxis
34
Q

TX for neurogenic shock

A
  • Atropine

- Vasopressors

35
Q

Which assessment to tell the effectivness of pantoprozole?

A

Check for occult blood in stool

36
Q

What 3 things do you give with a patient with septic shock?

A

1) Oxygen
2) Fluids
3) Antibiotics