SGL 4 Flashcards
What viral attachment protein is used in RSV?
G protein (on the virus) goes through random mutations.
Which class of neutralization is important in the neutralization in vivo?
It is important to neutralize with IgA as RSV attaches to MUCOSAL membranes.
What type of genome does norovirus possess?
linear single stranded positive sense RNA, icosahedral, not enveloped, nonsegmented
Where does the latent infection occur in HSV-1 and HSV-2?
HSV-1 is an infection primarily of the oropharyngeal mucosa, with latent infection occurring in the trigeminal ganglion while HSV-2 primarily infects the genital mucosa.
Where does the latent infection occur in HSV?
HSV, like all herpes viruses cause a lifelong, latent infection. In genital tract infections, the virus enters a latent state in the sacral nerve ganglia.
What type of genome does RSV possess?
linear, ssRNA negative sense, helical, enveloped, nonsegmented
What is the difference between Norovirus and Rotavirus in terms of age group?
Norovirus affect 5 year and older.
Rotavirus affect 5 years and younger.
Which of the following is a rapid test for laboratory diagnosis of HSV-2 infection?
Immunofluorescent staining of cells in scrapings of the lesions.
When does HSV-1 infection usually occur in otherwise healthy individuals?
What is the site of latent infection following a genital infection by HSV-2?A.B-lymphocyte B.Dermatonal nerveending C.Trigeminal nerve endings D.Sacral nerve ganglia14.Which of the following is a rapid test for laboratory diagnosis of HSV-2 infection? A.Cryo-electron microscopy B.Immunofluorescent staining of cells in scrapings of the lesions.C.Negative-staining D.Neutralization tests 15.When does HSV-1 infection usually occur in otherwise healthy individuals? A.Early adolescence B.Early adulthood C.Early childhood (1-24 months)
When does HSV-1 infection usually occur in otherwise healthy individuals?
Early childhood (1-24 months)
What is the most frequently recovered agent in patients with genital lesions in the industrialized world?
HSV-2
other recovered agents: Chlamydia trachomatis, Treponema pallidum, haemophilus ducreyi
The norovirus can survive for long periods outside a human host depending on the surface and temperature conditions: it can stay for weeks on hard surfaces and up to twelve days on contaminated fabrics FOMITES, and it can survive for months, maybe even years in contaminated still water.
Fomites represent an alternative source of infection by norovirus.
What do norovirus and respiratory syncytial virus have in common?
a single stranded RNA
What genome does HSV possess?
linear double stranded DNA, icosahedral, enveloped
