SEXUALLY TRANSMITTED DISEASES Flashcards
Gonococci and chlamydia induce a
discharge
Treponema pallidum induce a
mucosal sore
HPV induce
genital wart
Can be transmitted from mother to fetus
SYPHILIS
Disease starts as a painless sore in the genitals, rectum, & mouth
SYPHILIS
Spread from person to person via skin or mucous membrane contact with these sores
SYPHILIS
bacteria of SYPHILIS
Treponema pallidum
2-10weeksincubation
Initial contact
Primary chancre (painless)at site of infection,
Initial contact
First stage
Primary syphilis
Painless sore (chancre) - usually on the penis or
vagina, in the mouth or around the bottom
Primary syphilis
1-3months
Primary syphilis
Enlarged inguinal nodes but with spontaneous
healing
Primary syphilis
Second stage
Secondary syphilis
- Flu-like ,myalgia ,headache, rash but resolving
Secondary syphilis
- Rashes on the body-often on the palms of hands
and soles of feet (can persist for a few months)
Secondary syphilis
- 3-30years
Latent syphilis
- Dormantinliver&spleen
Latent syphilis
- This phase has no symptoms and may last a
decade or longer
Latent syphilis
- This phase has no symptoms and may last a
decade or longer
Latent syphilis
Third or late stage
Tertiary syphilis
- Neurosyphilis (general paralysis); cardiovascular, progressive destructive
- Gummasinskin,bones and joints
- Years later,some untreated patients experience
dementia, blindness, paralysis, heart failure, or syphilitic gummas
Tertiary syphilis
rubbery, swollen lesions that can occur in bones, in nervous tissue, or on the skin ; rarely develop in patients in countries where antimicrobial drugs are available.
Syphilitic gummas
rubbery, swollen lesions that can occur in bones, in nervous tissue, or on the skin ; rarely develop in patients in countries where antimicrobial drugs are available.
Syphilitic gummas
transmission symphilis
- Direct contact w/ syphilitic source: sex, person to person
● Pregnant mother can transmit to the unborn child
how to diagnose symphilis
Microhemagglutination assay against T. pallidum- MHA TP
Uses red blood cells that have been artificially coated
with Treponema antigens. It observes the agglutination of
the RBC upon RBC coated with Treponema antigen
Microhemagglutination assay against T. pallidum- MHA TP
Another STD, known to be as “theclap”
GONORRHEA
Bacterial condition that can affect the anus, throat, andurethra
GONORRHEA
Intimate contact is required for transmission
GONORRHEA
Transmitted during anal, oral, and vaginal sex
GONORRHEA
DOES GONORRHEA OCCURS IN HUMANS ONLY
YES
BACTERIA for GONORRHEA
GONORRHEA
Gram (-) diplococcus
GONORRHEA
virulence factors of gonorrhea
Pilus
● Proteins I & II
● LPS
● IgA protease
● Capsule
cell wall antigen composed of lipid A and sugar molecules
LPS
breaks down secretory IgA in mucus,
camouflaging bacterium from immune system
IgA protease
“THE SILENT DISEASE”
CHLAMYDIAL INFECTIONS
Can infect both men and women from , Spreads through unprotected vaginal, oral, and anal sex
CHLAMYDIAL INFECTIONS
Does not cause any symptoms and easily tx w/ antibiotics
CHLAMYDIAL INFECTIONS
nflammation of the epididymis
Epididymitis:
inflammation of the testes
Orchitis:
disease of the eye
Trachoma
severe form of
chlamydia STD in males and females
Lymphogranuloma venereum (LGV)
■ Most common
■ Formation of a genital lesion at the site of
infection: penis, urethra, scrotum, vagina, cervix, or external female genitalia
Lymphogranuloma venereum (LGV)
Followed by bubo (painful inflamed lymph node) - in the groin, fever, chills, anorexia, and muscle pain felt after chronic infection. Buboes may enlarge to the point that they rupture, producing draining sore
■ Caused by 3 strains of Chlamydia trachomatis
Lymphogranuloma venereum (LGV)
bacteria of CHLAMYDIAL INFECTIONS
Chlamydia trachomatis
Spore-likeandinfectious; infective form
Elementary bodies
Replicativestages
- Onlyseenwithin/insidethehostcells
Reticulate bodies
● Enter body through scrapes or cuts
CHLAMYDIAL INFECTIONS
Most reportable STD in the united states
CHLAMYDIAL INFECTIONS
It is a bacterial STD
CHANCROID
Diseaseischaracterizedbypainfulgenitalulcersthatmaybe
accompanied by inguinal lymphadenopathy and it is highly
contagious but very curable disease
CHANCROID
bacteria of CHANCROID
Haemophilus ducreyi
Each ducreyi usually enters the skin through disrupted mucosa and causes a local inflammatory reaction
CHANCROID