Sexual Medicine Flashcards

1
Q

Define Sex.

A

Assigned at birth - ‘Male/female’ - dependent on external genitalia

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2
Q

Define gender identity.

A

intrinsic send of being ‘male/female/alternative’

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3
Q

Define gender role/expression.

A

personality, appearance and behaviour (cultural & historical context)

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4
Q

What are primary sexual characteristics?

A

-present before, during and after puberty
M - penis, scrotum and testes
F - vagina, vulva, and ovaries

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5
Q

What are secondary sexual characteristics?

A

-present during and after puberty
M - enlargement of genitalia, lowering of voice, redistribution of fat and muscle tissue, pubic/facial/body/armpit hair
F - enlargement of genitalia, development of breasts, pubic and armpit hair

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6
Q

Define transgender.

A

Diverse gender variance including transsexual, genderqueer, agender.

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7
Q

Define Gender Dysphoria.

A

distress due to incongruence between gender identity and sex assigned at birth.

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8
Q

Define Transsexual.

A

individuals who seek to change or have changed their primary and/or secondary sex characteristics

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9
Q

Define Transmale.

A

assigned female at birth changing or changed to male role/body

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10
Q

Define Transfemale.

A

Male at birth changing or changed to female role/body

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11
Q

Define Sexual orientation.

A

Sex of person/s to whom sexual fantasies, arousal and activities are directed

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12
Q

when and how is sex determined in utero?

A
  • External genitalia and gonads - 8 weeks in utero
  • defeminisation and masculination caused by the Y chromosome (SRY gene) - testes development caused by testosterone and Mullerian inhibiting substance
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13
Q

When is gender identity bought about?

A
  • Second half of pregnancy
  • sexual differentiation in the brain caused by testosterone, oestrogen and genes = gender identity
  • HAPPENS INDEPENDENTLY OF SEX DETERMINATION
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14
Q

Some fun facts about gender identity and sex assignment.

A
  • 2 processes can be influenced independently
  • foetal gender identity remains permanent once influenced
  • lack of influence from the sex-of-rearing environment
  • Association with ASD
  • fMRI studies of MtF shows typical female response to pheromones and erotic stimuli
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15
Q

How would you manage someone wanting to transition from female to male? (Transmale)

A
  • assessment and diagnosis
  • social transition +/- psychotherapy/OT
  • fertility options
  • Androgens +/- GNrH analogue
  • Voice & communication Tx
  • Male chest reconstruction
  • hysterectomy & bilateral oophorectomy
  • phalloplasty/metoidoplasty
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16
Q

How would you manage someone wanting to transition from male to female? (Transfemale)

A
  • assessment and diagnosis
  • social transition +/- psychotherapy/OT
  • Fertility options
  • Oestrogens +/- antiandrogens
  • Voice and communication Tc
  • Facial hair removal
  • Vaginoplasty
  • augmentation mammoplasty
  • facial feminisation surgery
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17
Q

What’s the diagnostic criteria for Gender dysphoria according to the DSM-V?

A

a marked incongruence between one’s experienced/expressed gender and assigned gender or at least 6 months duration, as manifested by at least 2 of the following:

  • incongruence between one’s gender and primary/secondary sex characteristics
  • a strong desire to no longer have ones primary/secondary sex characteristics
  • A strong desire to have the primary/secondary characteristics of the opposite gender (other genders)
  • A strong desire to be of the other gender (or alternative from sex assigned at birth)
  • A strong desire to be treated as the other gender
  • A strong conviction that one’s typical feelings and reaction are that of the other gender

The condition is associated with clinically significant distress or impairment in social, occupational or other important areas of functioning.

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18
Q

Define Hypoactive Sexual Desire Disorder.

A
  • lack or loss of sexual desire. This is primary problem and not secondary to something else e.g. anxiety or ED.
  • Persistently deficient in sexual/erotic thoughts or fantasies and desire for sexual activity
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19
Q

What hormonal disorders could cause HSDD?

A

male - androgen deficient, hypogonadism, hyperprolactinaemia
female - androgen deficiency, hypothyroidism, hyperprolactinaemia, post pregnancy, addison’s disease.

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20
Q

What chronic medical conditions could cause HSDD?

A
  • Anaemia
  • obesity
  • CVD
  • DM
21
Q

What are some iatrogenic causes of HSDD?

A
  • anti-depressents
  • finesterides
  • orchidectomy
  • oral contraceptive
  • oral HRT
  • tamoxifen (bimd with testosterone)
  • Beta blockers in women
  • bilateral oophorectomy
22
Q

What psychological factors could cause HSDD?

A
  • psych conditions - anxiety, depression etc
  • psychological experiences - environmental, life events, previous trauma
  • body image disorder
  • couple script problems
  • erotic dissatisfaction
  • couple relationship problems
23
Q

What are the treatment options for HSDD?

A
  • medical - testosterone injection/patch/buccal/implants
  • behavioural intervention - sexual growth programme
  • other psychotherapy - dynamic, CBT, systemic
24
Q

Define erectile dysfunction.

A

-difficulty developing or maintaining an erection suitable for satisfactory intercourse

25
Q

What are some organic causes of ED?

A
  • hormonal: androgen deficiency, High prolactin
  • medical disorders: CVD, DM, neuro disease
  • iatrogenic: post prostate surgery, SSRUs anti-HTNs
  • age related changes
  • ineffective sexual stimuli
  • pain
  • veno-occlusice disorder
26
Q

What are some psychological causes of ED?

A
  • depression, anxiety, substance misuse
  • performance anxiety
  • couple script problems
  • relationship problems or previous relationship problems
  • educational matters
  • cultural or religious matters
27
Q

What medical treatment options are there for ED?

A
  • sildenafil
  • avanafil
  • Intra cavernosal injections - alprostadil
  • intraurethral - adaprostadil
28
Q

What are some non-medical treatments for ED?

A
  • vacuum devices
  • penile/scrotal rings
  • stimulants - ehancinglubricants or vibrators
  • kegel exercises
  • individual sexual and/or couple therapy
29
Q

Define female sexual arousal disorder.

A
  • failure of genital response - vaginal dryness or failure of lubrication
  • absent or reduced interest or arousal during sexual activity
30
Q

Define female orgasmic disorder.

A

-orgasm either does not occur or is markedly delayed

31
Q

What can cause female orgasmic disorder?

A
  • chronic medical conditions - CVD, DM, neurological disease, renal/liver problems
  • hormonal disorders - oestrogen and/or androgen insufficiency, hypothyroidism
  • pelvic floor weakness or damage
  • ageing
  • SSRIs
32
Q

What are some psychological causes of female orgasmic disorder?

A
  • psych condition - anxiety, depression, substance misuse
  • previous abuse
  • couple script problems
  • couple relationship problems
  • cultural and religious issues
  • lack of understanding
  • environmental factors
  • Stress
33
Q

How could you treat vaginal dryness?

A

topical oestrogen

34
Q

How can menopause affect sexual dysfunction?

A
  • vaginal or pelvic pain
  • vaginal atrophy
  • dryness
  • change in self image, mood, memory, cognition
  • changes in desire
  • physical discomfort - sleeplessness, night sweats
35
Q

Define rapid ejaculation.

A

inability to control ejaculation sufficiently for both partners to enjoy sexual interaction

36
Q

What are some physiological causes of rapid ejaculation?

A
  • genetics - neuroreceptor sensitivity
  • penile hypersensitivity
  • hyperthyroidism
  • prostatitis
  • co-morbid sexual problems ED
  • sympathomimetic medication
37
Q

what are some psychological causes of rapid ejaculation?

A
  • anxiety states
  • early learned experiences
  • lack of experience/infrequent sexual activity
  • psychosocial and environmental factors
  • relationship issues
  • partner issues e.g. pain
38
Q

What treatments are available for rapid ejaculation?

A
  • topical anaesthetic
  • dapoxetine
  • couple psychotherapy - education, permission giving, normalising
  • behavioural intervention - stop/start, practice point of inevitability, kegel exercises.
39
Q

Define delayed ejaculation.

A

on almost or all occasions either generalised or situational without the individual desiring delay:
-marked delay in ejaculation
-marked infrequency or absence of ejaculation
may be lifelong or acquired, mild, moderate or severe

40
Q

What are some physiological causes of delayed ejaculation?

A
  • cogenital disorders
  • trauma or surgery
  • Age
  • infectious disease
  • neurological disorder
  • depression
  • medicatio - SSRI, phenothiazines, thiazides, some alpha blockers
  • low testosterone
  • EXCLUDE RETROGRADE EJACULATION
41
Q

What are some psychological aetiologies of Delayed ejaculation?

A
  • insufficient stimulation/poor sexual arousal
  • masturbation technique
  • individual vulnerability e.g. poor body image, Hx of sexual or emotional abuse
  • relationship factors e.g. poor communication, desire discrepancies
  • partner issues
  • disguised desire disorder
  • secondary to other sexual problems e.g. pain disorder
42
Q

How do you investigate prolonged ejaculation?

A
  • Physical examination - testes, epididymis, vasa, prostate
  • bloods - FBC, glucose, testosterone, B12, Folate, PSA,
  • Urine sample for presence of spematozoa or fructose (retrograde ejaculation)
43
Q

How do you treat delayed ejaculation?

A
  • PSGP
  • individual therapy
  • couple therapy
  • kegel exercises
  • use of vibration/superstimulation
44
Q

Define Vaginismus.

A

Spasm of the pelvic floor muscles that surround the vagina, causing occlusion of the vaginal opening. Penile entry is either impossible or painful.

  • marked fear regarding penetration
  • marked tensing or tightening of pelvic floor during attempted penetration
45
Q

What physiological factors may cause vaginismus?

A
  • medical conditions where vulva is sore to touch (thrush)
  • other pain conditions where pain is anticipated
  • FGM
  • congenital abnormality
46
Q

What psychological factors may cause vaginismus?

A
  • misinformation and mistaken beliefs: too small, no opening, first WILL be painful
  • religious or cultural issues
  • fear of pregnancy
  • previous abuse or trauma
  • fear or dislike of partner
  • relationship dissatisfaction
  • situational
47
Q

What interventions are there for vaginismus?

A
  • CBT
  • self exploration, mirror examination
  • kegel exercises
  • vaginal trainers
  • personal sexual growth programme
48
Q

What physiological are some physiological causes of dyspareunia?

A
  • manipulation - infection, injury, irritation, lesions, hypersensitivty
  • pain on entry - episiotomy/circumcision, recurrent infection, herpes, allergies, bartholins cyst, intersitital cystitis, urethritis, vaginal atrophy, menopause, post radiotherapy, poor lube
  • mid-deep vaginal pain - Endometriosis, congenital shortened vagina, fixed uterine retroversion, pelvic tumours, surgical adhesion’s, IBS, constipation