Sex hormone responsive conditions Flashcards

1
Q

What sex hormone has weak oestrogenic, progestogenic and androngenic activity

A

Tibolone

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2
Q

What does HRT increase the risk of?

A

Stroke, VTE, endometrial cancer, breast cancer, ovarian cancer, CHD (if on combined HRT >10 years after menopause)

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3
Q

How long before surgery should HERt be stopped?

A

4 - 6 weeks

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4
Q

Natural estrogens

A

Estradiol, estrone, Estriol

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5
Q

Synthetic estrogens

A

ethinylestradiol, mestranol

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6
Q

What are vasomotor symtpoms?

A

Hot flushes, night sweats

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7
Q

If a women without a uterus, what hormone should be offered for HRT>

A

Oestrogen alone continuously

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8
Q

Peri-menopausal women or those <12 months after last period cannot have what form of HRT

A

oestrogen and progesterone

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9
Q

What hormone reduced the risk of endometrial cancer?

A

Progesterone

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10
Q

First line therapy for Mennorrhagia

A

Levonorgesterol releasing IUD

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11
Q

Ethinylestradiol should be cautioned when BMI is?

A

30 (avoid if 35)

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12
Q

If a patient is >35 and smokes can they have ethinylestradiol?

A

no - BNF advises to avoid

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13
Q

If vommiting occurs within 2 hours of taking POC what should the patient do?

A

Take another tablet asap. If not taken within 3 hours of the normal time additional precautions should be taken and for 2 days after recovery

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14
Q

If a progesterone pil is not taken and its 3 hours past usual adminsitration time, what is the issue?

A

Contraceptive control may be lost

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15
Q

How long after birth can POC be restarted?

A

21 days

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16
Q

Clomifene is an ovulation stimulant used in infertility. How many cycles can it be used for maximum?

A

6 cycles - risk of ovarian cancer

17
Q

Dustaride and finasteride are used for what?

A

BPH

18
Q

what indication is low strength finasteride used for

A

male pattern baldness