Sex diseases Flashcards
1
Q
Androgen Insensitivity
A
46XY, Have normal female external genetilia, No Ovaries or tubes, Testes present in the abdomen or inguinal canal
2
Q
Congenital Adrenal Hyperplasia
A
Normal Ovarian tissue, but ambiguous or male external genetilia
3
Q
47XXY
A
Kleinfelter Synd, Male but has gonadaldysgenesis
4
Q
DAX1 Duplication
A
Reduce testis and build ovaries… Both
5
Q
X inactivation
A
Regulated by XIST gene on the Inactive X.. Form Barr bodies
6
Q
XIST
A
Active on the Inactivated X. XIST -> RNA transcript that is not translated into protein. The inactive chromosome is then coated with this transcript
7
Q
Mullerian Inhibiting Factor
A
Released by Testes. Encoded by AMH Gene (Anti-Mullerian Hormone) It inhibits the formation og mullerian tubes and ovaries
