Sex and the Single Chromosome Flashcards

1
Q

What are autosomes?

A

Have nothing to do with sex

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2
Q

What chromosomes do females have?

A
  • 22 pairs of autosomes and XX
  • All gametes 22A + X
  • Homogametic
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3
Q

What chromosomes do males have?

A
  • 22 pairs of autosomes and XY
  • Half gametes 22A + X and half 22A + Y
  • Heterogametic
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4
Q

Why do sex ratios balance out?

A
  • Rare sex has an evolutionary advantage to get genes into the next generation
  • Ratio balances back out
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5
Q

What are four human chromosome abnormalities?

A
  • 44AOY: Dies
  • 44AXO: Turner’s syndrome
  • 44AXXY: Klinefelter’s syndrome
  • 44AXXX: Triple X
  • 44AXYY: Double Y
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6
Q

What is Turner’s syndrome?

A
  • Female phenotype
  • Sterile
  • Late sexual maturity
  • Webbing of skin on neck
  • Upturned fingernails
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7
Q

What is Klinefelter’s syndrome?

A
  • Variable male phenotype

- Sterile

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8
Q

What is triple X?

A
  • Normal female phenotype
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9
Q

What is double Y?

A
  • Normal male phenotype
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10
Q

How is sex determined?

A
  • By the Sex Determining Region (SRY) gene

- Default development is female

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11
Q

What is required for males?

A
  • Testis determining factor: SRY locus on Y chromosome

- Receptor for male steroid hormones: androgen receptor on X chromosome

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12
Q

What genes are involved in sex linkage?

A

Genes on the part of X and Y chromosomes that do not pair

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13
Q

Why is sex disadvantageous?

A

Two-fold cost of sex

  • Female that has only females will get more genes into the next generation
  • Sexual female will have half children who may not pass on her genes directly

Require a mate

  • Look for mates
  • Compete for mates
  • Finding mates at low population density
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14
Q

What is anisogamy?

A

Difference in the size of eggs and sperm

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15
Q

Why is anisogamy important?

A
  • Large gametes: more food and more robust
  • Small gametes: can produce more of them
  • Intermediate size has no advantage
  • Outcome is evolutionary arms race
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16
Q

What are the benefits of sex?

A
  • DNA repair
  • Muller’s ratchet
  • The tangled bank
  • The Red Queen hypothesis
17
Q

What are the benefits of DNA repair

A
  • Proof reading when homologous chromosomes pair

- BUT could happen without sexual reproduction

18
Q

What is the consideration of Muller’s ratchet

A
  • Prevents accumulation of mutations
  • Undesirable mutations are more likely than favourable ones
  • Sex allows elimination of undesirable mutations and accumulation of favourable ones
  • BUT the good of the species argument doesn’t work because evolution works on an individual basis
19
Q

What is the benefit of the tangled bank?

A

Variable gametes mean:

  • Offspring won’t compete with parents or each other
  • Able to fit into ecological niches
20
Q

What is the Red Queen hypothesis?

A
  • Pathogens and parasites are small compared to the organisms they infect
  • Larger organisms take longer to replicate
  • Need variability to defeat pathogens
  • Have to ‘run faster to stay in the same place’
21
Q

How is it thought the Y chromosome will evolve?

A
  • Y chromosome has very few genes (mostly just SRY)
  • Evolutionary pressure to lose functional genes to other chromosomes where they are protected by diploidy
  • Hypothesised Y may eventually be lost