Severson CV Development Vignettes Flashcards
What is the most common type of defect associated with the cardiac septa? A. Membranous type VSD B. Muscular type VSD C. Patent foramen ovale D. Primary type ASD E. Secondary type ASD
A
What structures fuse to close the primary foramen?
A. Membranous and muscular parts of the interventricular septum.
B. Membranous part of the interventricular septum and the endocardial cushions.
C. Primary septum and the endocardial cushions.
D. Primary septum and the septum secundum.
E. Secondary septum and the endocardial cushions.
C
Which of the following statements regarding transposition of the great arteries (TGA) is CORRECT?
A. This abnormality is more common in female than male infants.
B. Most infants with this abnormality survive for several months without intervention; surgical repair is done when they are about five years old.
C. This abnormality is not amenable to surgical correction.
D. This abnormality is caused by unequal partitioning of the bulbus cordis and truncus arteriosus coupled with an incomplete interventricular septum.
E. This abnormality is due to failure of the aorticopulmonary septum to develop a spiral course.
E
The tetralogy of Fallot is an association of anomalies that arises through a pathogenetic cascade of malformations in the heart. Which of the following anomalies would be considered to be the final defect in this pathogenetic cascade?
A. Constricted subpulmonary orifice
B. Enlarged right ventricle
C. Pulmonary stenosis
D. Rightward displacement of the aorta (overriding aorta)
E. Ventricular septal defect
B
In humans, the left fourth aortic arch gives rise to a portion of which of the following structures? A. Arch of the aorta B. Ductus arteriosus C. Left common carotid artery D. Left external carotid artery E. Left subclavian artery
A
In a particular newborn infant, a substantial volume of blood takes the following route from the left ventricle to the lower limbs: ascending aorta > brachiocephalic artery > right subclavian artery > right internal thoracic artery > right anterior intercostal arteries > right posterior intercostal arteries > descending aorta. What diagnosis is probably likely for this newborn infant? A. Coarctation of the aorta B. Double aortic arch C. Patent ductus arteriosus D. Patent foramen ovale E. Tetralogy of Fallot
A
Transposition of the great arteries was diagnosed in a male infant with obvious cyanosis and mild tachypnea (rapid breathing). This condition results from which of the following?
A. Abnormal resorption of the primary septum
B. Abnormal transformation of the sixth aortic arches
C. Failure of the endocardial cushions to fuse
D. Faulty partitioning of the bulbus cordis and truncus arteriosus
E. Involution of the ductus arteriosus
D
What is the most common congenital anomaly of the heart and great vessels associated with the congenital rubella syndrome? A. Atrial septal defect B. Coarctation of the aorta C. Patent ductus arteriosus D. Tetralogy of Fallot E. Ventricular septal defect
C
Which of the following is NOT associated with the tetralogy of Fallot? A. Hypertrophy of the right ventricle B. Interventricular septal defect C. Overriding aorta D. Patent foramen ovale E. Pulmonary stenosis
D
What developmental structure contributes to the formation of the membranous part of the interventricular septum and fuses with the aorticopulmonary septum? A. Crista terminalis B. Endocardial cushions C. Interatrial septum II D. Ligamentum arteriosum E. Transverse sinus
B
Which aortic arch gives rise to the proximal part of the right pulmonary artery?
A. Left sixth aortic arch (proximal portion)
B. Left sixth aortic arch (distal portion)
C. Right third aortic arch (proximal portion)
D. Right fourth aortic arch (entire arch)
E. Right sixth aortic arch (proximal portion)
E
Which vessel(s) in the fetal circulation carries blood with the highest oxygen content?
A. Arteries to the head and upper extremities
B. Dorsal aorta
C. Ductus arteriosus
D. Pulmonary veins
E. Umbilical vein
E
Which veins drain the yolk sac? A. Azygos veins B. Cardinal veins C. Intercostal veins D. Umbilical veins E. Vitelline veins
E
Where do the vitelline veins, umbilical veins and cardinal veins directly drain? A. Aortic arches B. Bulbus cordis C. Primitive atrium D. Sinus venosus E. Ventricle
D
The embryonic umbilical vein develops into what structure during development of the postnatal circulation? A. Ductus arteriosum B. Ligamentum arteriosum C. Ligamentum teres D. Ligamentum venosum E. Superior vesical artery
C
The cardinal veins in the fetus:
A. are formed from splanchnic mesoderm.
B. completely disappear by the time of birth.
C. contribute to the superior and inferior vena cava.
D. drain the developing intestinal tract.
E. travel through the umbilical cord in conjunction with the umbilical artery.
C
What structure is formed by the right horn of the sinus venosus? A. Aorta B. Coronary atrium C. Left atrium D. Pulmonary trunk E. Right atrium
E
Which of the following are responsible for formation of the truncobulbar ridges?
A. Endocardial cushions
B. Interatrial and interventricular septa
C. Neural crest mesenchyme
D. Somatic mesoderm
E. Yolk sac mesoderm
C
The endocardial cushions contribute to the formation of what structure?
A. Aorticopulmonary septum
B. Interatrial septum II
C. Membranous part of interventricular septum
D. Muscular part of interventricular septum
E. Urorectal septum
C
The ductus venosus shunts blood from the:
A. inferior vena cava to the umbilical arteries.
B. left umbilical vein to the inferior vena cava.
C. left umbilical vein to the pulmonary artery.
D. left umbilical vein to the pulmonary trunk.
E. pulmonary trunk to the aorta.
B
Which of the following vessels is NOT derived from the cardinal veins? A. Azygos veins B. Common iliac vein C. Renal veins D. Superior mesenteric vein E. Superior vena cava
D
What term is used to refer to abnormal heart development in which the aorta arises from the right ventricle and the pulmonary trunk arises from the left ventricle?
A. Dextrocardia
B. Persistent truncus arteriosus
C. Pulmonary infundibular stenosis (narrowing)
D. Transposition of the great vessels (TGA)
E. Ventricular septal defect
D
Which of the following would NOT be responsible for development of an atrial (interatrial) septal defect?
A. An incompetent foramen ovale
B. Excessive resorption of the tissue around the secondary foramen
C. Failure of resorption of the dorsal mesocardium
D. Failure of the endocardial cushions to form
E. Failure of the primary septum to fuse with the endocardial cushions
C
The foramen ovale and the valve of the foramen ovale are derived, respectively, from:
A. endocardial cushions, membranous interventricular septum.
B. interatrial septum I, interatrial septum II.
C. interatrial septum II, interatrial septum I.
D. membranous interventricular septum, endocardial cushions.
E. membranous interventricular septum, muscular interventricular septum
C
A secondary ASD was detected in a young child. This congenital defect:
A. includes defects of the fused endocardial cushions.
B. is located near the superior vena cava.
C. occurs more frequently in males than in females.
D. usually results from abnormal resorption of the primary septum.
E. usually causes death in early childhood.
D